ContextCurrent evidence that breastfeeding is beneficial for infant and child health is based
exclusively on observational studies. Potential sources of bias in such studies have led to …

Background The optimal hemoglobin threshold for erythrocyte transfusions in critically ill
children is unknown. We hypothesized that a restrictive transfusion strategy of using packed red …

Context The evidence that breastfeeding improves cognitive development is based almost
entirely on observational studies and is thus prone to confounding by subtle behavioral …

Background Self-management interventions improve various outcomes for many chronic
diseases. The definite place of self-management in the care of chronic obstructive pulmonary …

Background The use of hyperbaric oxygen for children with cerebral palsy has spread
worldwide, despite little scientific evidence of efficacy. We did a randomised trial to assess the …

Objective To conduct a systematic review of reports on the physical and psychological effects
of Tai Chi on various chronic medical conditions. Data Sources Search of 11 computerized …

Background: The evidence that breastfeeding protects against obesity and a variety of chronic
diseases comes almost entirely from observational studies, which have a potential for bias …

Background: Chronic neuropathic pain affects 1%–2% of the adult population and is often
refractory to standard pharmacologic treatment. Patients with chronic pain have reported using …

Background Opinions and recommendations about the optimal duration of exclusive breastfeeding
have been strongly divided, but few published studies have provided direct evidence …

This pilot randomized controlled clinical trial of patients with ARDS was implemented to study
the impact of inhaled nitric oxide (inhNO) on lung function, morbidity, and mortality. Thirty …