… Author links open overlay panel Jean K. Mah a b , Lawrence Korngut a c , Jonathan Dykeman
a c d e , Lundy Day a , Tamara Pringsheim a b , … JK Mah, K. Selby, C. Campbell, et al. …

Background: The muscular dystrophies are a heterogeneous group of genetic muscle diseases
with variable distribution of weakness and mode of inheritance.Methods: We previously …

Duchenne muscular dystrophy (DMD) is the most common form of muscular dystrophy in
childhood. It is caused by mutations of the DMD gene, leading to progressive muscle weakness…

Background Glucocorticoid treatment is recommended as a standard of care in Duchenne
muscular dystrophy; however, few studies have assessed the long-term benefits of this …

Background Duchenne muscular dystrophy (DMD) is a severe, progressive, and rare
neuromuscular, X-linked recessive disease. Dystrophin deficiency is the underlying cause of …

Background The full spectrum of clinical manifestations and outcome, and the potential
importance of regional or demographic features or viral triggers in paediatric multiple sclerosis (…

Background HLA-DRB1*15 genotype, previous infection with Epstein-Barr virus, and
vitamin D insufficiency are susceptibility factors for multiple sclerosis, but whether they act …

Background The senses of touch and proprioception evoke a range of perceptions and rely
on the ability to detect and transduce mechanical force. The molecular and neural …

Serum biomarkers in Duchenne muscular dystrophy (DMD) may provide deeper insights into
disease pathogenesis, suggest new therapeutic approaches, serve as acute read-outs of …

Introduction: ACE‐031 is a fusion protein of activin receptor type IIB and IgG1‐Fc, which
binds myostatin and related ligands. It aims to disrupt the inhibitory effect on muscle …