Background . Since 2002, an epidemic of Clostridium difficile–associated-diarrhea (CDAD)
associated with a high case-fatality rate has involved >30 hospitals in the province of Quebec…

Background: Recent reports suggest that Clostridium difficile colitis may be evolving into a
more severe disease. During the second half of 2002 we noted an increase in the number of …

Background: Since 2002 an epidemic of Clostridium difficile–associated disease (CDAD)
caused by a hypervirulent toxinotype III ribotype 027 strain has spread to many hospitals in …

Thirty years after the discovery of HIV-1, the early transmission, dissemination, and establishment
of the virus in human populations remain unclear. Using statistical approaches applied …

Background Clinicians who treat patients with Clostridium difficile–associated diarrhea (CDAD)
in Quebec, Canada, have noted an apparent increase in the proportion of patients who …

… a physician in a bush hospital in Zaire, Jacques Pépin looks back to the early twentieth-century …
Jacques Pépin is Professor in the Department of Microbiology and Infectious Diseases at …

Objectives: To determine whether emergency colectomy reduces mortality in patients with
fulminant Clostridium difficile-associated disease (CDAD), and to identify subgroups of …

Using 42 isolates contributed by laboratories in Canada, The Netherlands, the United Kingdom,
and the United States, we compared the results of analyses done with seven Clostridium …

A series of measures were implemented, in a secondary/tertiary-care hospital in Quebec, to
control an epidemic of nosocomial Clostridium difficile-associated disease (n-CDAD) caused …

BACKGROUND: An increasing risk of infectious complications following transrectal
ultrasound–guided prostate needle biopsy (PNB) has been observed recently in some centers. …