Background: Data on the association between subclinical thyroid dysfunction and coronary
heart disease (CHD) and mortality are conflicting. Purpose: To summarize prospective …

Background Data from prospective cohort studies regarding the association between subclinical
hyperthyroidism and cardiovascular outcomes are conflicting. We aimed to assess the …

Importance The benefit of thyroid hormone therapy for subclinical hypothyroidism is uncertain.
New evidence from recent large randomized clinical trials warrants an update of previous …

ContextDespite the equivocal outcomes of randomized controlled trials, general clinical
opinion favors screening and treatment of elderly individuals with subclinical thyroid disorders.…

Context Data regarding the association between subclinical hypothyroidism and cardiovascular
disease outcomes are conflicting among large prospective cohort studies. This might …

Background: muscle wasting is associated with a detrimental outcome in older people.
Muscle strength measurements could be useful as part of a clinical evaluation of oldest old …

Background Successful aging is a worldwide aim, but it is less clear which indicators
characterize elderly persons as successfully aged. We explored the meaning of successful aging …

An elevated level of C-reactive protein is a strong predictor of cardiovascular events in elderly
persons. Whether C-reactive protein has direct adverse vascular effects or is a marker of …

Background— American College of Cardiology/American Heart Association guidelines for
the diagnosis and management of heart failure recommend investigating exacerbating …

Background: Poor muscular strength has been shown to be associated with increased
morbidity and mortality in diverse samples of middle-aged and elderly people. However, the …