Multiple focal nodular hyperplasia of the liver associated with vascular malformations of various organs and neoplasia of the brain: a new syndrome.

IR Wanless, S Albrecht, J Bilbao, JV Frei… - Modern pathology: an …, 1989 - europepmc.org
Focal nodular hyperplasia (FNH) is a lesion of the liver in which a large anomalous artery is
located within a region of hyperplastic hepatic parenchyma. Patients with FNH commonly …

Alkylation of deoxyribonucleic acid in vivo in various organs of C57BL mice by the carcinogens N-methyl-N-nitrosourea, N-ethyl-N-nitrosourea and ethyl …

JV Frei, DH Swenson, W Warren… - Biochemical …, 1978 - portlandpress.com
1. Methods were developed for analysis of alkylpurines, O2-alkylcytosines, and representative
phosphotriesters [alkyl derivatives of thymidylyl(3′-5′)thymidine], in DNA alkylated in …

Hepatic copper and metallothionein distribution in Wilson's disease (hepatolenticular degeneration).

NO Nartey, JV Frei, MG Cherian - Laboratory investigation; a journal …, 1987 - europepmc.org
Wilson's disease is a rare inherited disorder of copper (Cu) metabolism characterized by the
deposition of Cu in the liver, brain, and cornea. The levels of metallothionein (MT), Cu, and …

The fine structure of the basement membrane in epidermal tumors

JV Frei - The Journal of cell biology, 1962 - rupress.org
Epidermal tumors were induced in Swiss female mice by a topical application of 9,10-dimethyl-1,2-benzanthracene
solution followed by repeated applications of croton oil solutions. …

Induction of liver cell adenomata in the rat by a single treatment with N-methyl-N-nitrosourea given at various times after partial hepatectomy

VM Craddock, JV Frei - British Journal of Cancer, 1974 - nature.com
A single treatment of adult animals with the potent carcinogen NMU was known to induce
tumours in a wide variety of organs, with the notable exception of liver. Administration of NMU …

Granulomatous hepatitis and fever of unknown origin: an 11-year experience of 23 cases with three years' follow-up

DE Zoutman, ED Ralph, JV Frei - Journal of clinical …, 1991 - journals.lww.com
Granulomatous hepatitis is a common cause of fever of unknown origin in up to 13% of
patients with prolonged ever. Attempts to define an exact etiology of the granumatous hepatitis …

Some mechanisms operative in carcinogenesis a review

JV Frei - Chemico-Biological Interactions, 1976 - Elsevier
Multiple factors contribute to the development of neoplasia. Sometimes a single agency can
bring about a tumour if it has many different effects, but at other times a tumour arises more …

The correlation of promotion of tumour growth and of induction of hyperplasia in epidermal two-stage carcinogenesis.

JV Frei, P Stephens - British Journal of Cancer, 1968 - ncbi.nlm.nih.gov
MATERIALS AND METHODS The mice used in the experiments were 6-10 week old Swiss
mice randomly bred in our laboratory. In one experiment inbred Swiss mice (Ball, Huh and …

Low serum 25-hydroxyvitamin in hereditary hemochromatosis: relation to iron status

LH Chow, JV Frei, AB Hodsman, LS Valberg - Gastroenterology, 1985 - Elsevier
Under normal conditions, vitamin D absorbed from the diet or synthesized in. the skin is
transported to the liver where it undergoes hydroxylation. The purpose of this study was to …

Management of adenocarcinoma in a columnar-lined esophagus

…, S Sullivan, LS Valberg, WC Watson, JV Frei… - The Annals of thoracic …, 1985 - Elsevier
Of 89 patients diagnosed between 1973 and 1983 as having at least 3 cm of columnar-lined
esophagus, 22 were found to have adenocarcinoma. There was no difference in sex ratio, …