Objective To estimate the prevalence of gout and hyperuricemia based on the latest nationally
representative sample of US men and women (National Health and Nutrition Examination …

A major challenge in human genetics is to devise a systematic strategy to integrate disease-associated
variants with diverse genomic and biological data sets to provide insight into …

Researchers have recently made advances in defining the pathogenesis of gout, including
elucidating its risk factors and tracing the molecular mechanisms of renal urate transport and …

Background Limited prospective information exists on the relation between obesity and
weight change and the risk of gout. Similarly, both hypertension and diuretic use have been …

Background Methotrexate is the most frequent choice of disease-modifying antirheumatic
therapy for rheumatoid arthritis. Although results of studies have shown the efficacy of such …

Background The association between alcohol consumption and risk of gout has been
suspected since ancient times, but has not been prospectively confirmed. Additionally, potential …

PURPOSE: The link between hyperuricemia and insulin resistance has been noted, but the
prevalence of the metabolic syndrome by recent definitions among individuals with …

Background— Although gout and hyperuricemia are related to several conditions that are
associated with reduced survival, no prospective data are available on the independent …

Background Various purine-rich foods and high protein intake have long been thought to be
risk factors for gout. Similarly, the possibility that the consumption of dairy products has a …

Objective To determine the prevalence of metabolic syndrome among patients with gout and
to examine the association between the 2 conditions in a nationally representative sample …