Background: Depression is a major cause of morbidity and mortality in children and adolescents.
To date, randomized, controlled, double-blind trials of antidepressants (largely tricyclic …

OBJECTIVE: To compare paroxetine with placebo and imipramine with placebo for the
treatment of adolescent depression. METHOD: After a 7- to 14-day screening period, 275 …

BACKGROUND:: This report presents results from the acute treatment phase of a clinical
trial designed to confirm efficacy of a fixed dose of 20 mg of fluoxetine in children and …

OBJECTIVE: To develop effect sizes for 3 mood stabilizers-lithium, divalproex sodium, and
carbamazepine-for the acute-phase treatment of bipolar I or II disorder, mixed or manic …

OBJECTIVE: In 1998, the Texas Department of Mental Health and Mental Retardation
developed algorithms for medication treatment of attention-deficit/hyperactivity disorder (ADHD). …

Systematic research and practice guidelines addressing preschool psychopharmacological
treatment in very young children are limited, despite evidence of increasing clinical use of …

Objective: The authors sought to identify predictors of self-harm adverse events in treatment-resistant,
depressed adolescents during the first 12 weeks of treatment. Method: Depressed …

Objective: The aim of this study was to present the reliability and validity of the Children's
Depression Rating Scale–Revised (CDRS-R) in the adolescent age group. Method: …

OBJECTIVE: This article presents the results from a prospective, randomized, double-blind,
placebo-controlled trial of escitalopram in adolescent patients with major depressive disorder…

Objective. To examine the role of self-reported depressive symptoms in predicting hospitalization
for complications of diabetes mellitus over a period of up to 2 years. Study Design. Two …