Brain mechanisms of propofol-induced loss of consciousness in humans: a positron emission tomographic study

P Fiset, T Paus, T Daloze, G Plourde… - Journal of …, 1999 - Soc Neuroscience
In the present study, we used positron emission tomography to investigate changes in regional
cerebral blood flow (rCBF) during a general anesthetic infusion set to produce a gradual …

Patient State Index: titration of delivery and recovery from propofol, alfentanil, and nitrous oxide anesthesia

…, HJ Lemmens, ET Pierce, G Plourde… - The Journal of the …, 2002 - pubs.asahq.org
Background The Patient State Index (PSI) uses derived quantitative electroencephalogram
features in a multivariate algorithm that varies as a function of hypnotic state. Data are …

Physostigmine reverses propofol-induced unconsciousness and attenuation of the auditory steady state response and bispectral index in human volunteers

…, SB Backman, V Bonhomme, G Plourde… - The Journal of the …, 2000 - pubs.asahq.org
Background It is postulated that alteration of central cholinergic transmission plays an
important role in the mechanism by which anesthetics produce unconsciousness. The authors …

Impact of dietary fat content and fat oxidation on energy intake in humans

A Tremblay, G Plourde, JP Despres… - The American journal of …, 1989 - Elsevier
Three studies were performed to assess the effects of a high-fat diet and exercise-induced
changes in fat oxidation on energy intake in humans. In the first study the short-term effect of a …

Cortical processing of complex auditory stimuli during alterations of consciousness with the general anesthetic propofol

G Plourde, P Belin, D Chartrand, P Fiset… - The Journal of the …, 2006 - pubs.asahq.org
Background The extent to which complex auditory stimuli are processed and differentiated
during general anesthesia is unknown. The authors used blood oxygenation level-dependent …

Human auditory steady-state responses: the effects of recording technique and state of arousal

…, MS John, DW Purcell, G Plourde - Anesthesia & …, 2003 - journals.lww.com
IMPLICATIONS: Auditory steady-state responses to stimuli presented at rates near 40 Hz
can be used to monitor anesthesia. These responses can be quickly and reliably recorded …

Ketamine increases the amplitude of the 40-Hz auditory steady-state response in humans.

G Plourde, J Baribeau… - British journal of …, 1997 - academic.oup.com
The auditory middle latency response (AMLR) and the 40-Hz auditory steady-state response
(40-Hz ASSR) are evoked potentials which possibly arise from the same generators in the …

[HTML][HTML] Impact of obesity on glucose and lipid profiles in adolescents at different age groups in relation to adulthood

G Plourde - BMC family practice, 2002 - Springer
Background As obesity is rapidly becoming a major medical and public health problem, the
aim of our study was to determine: 1) if obesity in Caucasian adolescents at 5 different …

Preventing and managing pediatric obesity. Recommendations for family physicians.

G Plourde - Canadian Family Physician, 2006 - cfp.ca
OBJECTIVE To review the evidence on prevention and management of childhood obesity and
to offer suggestions for family physicians. QUALITY OF EVIDENCE Articles were obtained …

Dose-dependent effects of propofol on the central processing of thermal pain

RK Hofbauer, P Fiset, G Plourde… - The Journal of the …, 2004 - pubs.asahq.org
Background Anatomic and physiologic data show that multiple regions of the forebrain are
activated by pain. However, the effect of anesthetic level on nociceptive input to these regions …