The safety of combining angiotensin-converting-enzyme inhibitors with angiotensin-receptor blockers in elderly patients: a population-based longitudinal analysis

FA McAlister, J Zhang, M Tonelli, S Klarenbach… - CMAJ, 2011 - Can Med Assoc
Background The risks associated with using an angiotensin-converting-enzyme (ACE)
inhibitor and an angiotensin-receptor blocker together are unclear. This study was designed …

[HTML][HTML] Combining angiotensin receptor blockers with ACE inhibitors in elderly patients

S Anand, MK Tamura - American journal of kidney diseases: the …, 2012 - ncbi.nlm.nih.gov
Angiotensin-converting enzyme (ACE) inhibitors decrease mortality and cardiovascular
events in patients with cardiovascular disease or high-risk diabetes and slow the …

[HTML][HTML] Comparative effectiveness of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers in terms of major cardiovascular disease …

SC Chien, SM Ou, CJ Shih, PW Chao, SY Li, YJ Lee… - Medicine, 2015 - journals.lww.com
Renin and aldosterone activity levels are low in elderly patients, raising concerns about the
benefits and risks of angiotensin-converting-enzyme inhibitors (ACEIs) and angiotensin II …

Meta-analysis of randomized trials on the efficacy and safety of angiotensin-converting enzyme inhibitors in patients≥ 65 years of age

C Bavishi, M Ahmed, V Trivedi, AR Khan… - The American journal of …, 2016 - Elsevier
The comparative efficacy and safety of angiotensin-converting enzyme inhibitors (ACEIs)
with other agents in patients≥ 65 years of age with cardiovascular diseases or at-risk are …

Current guidelines for using angiotensin-converting enzyme inhibitors and angiotensin II–receptor antagonists in chronic kidney disease: is the evidence base …

AM O'Hare, JS Kaufman, KE Covinsky… - Annals of internal …, 2009 - acpjournals.org
Angiotensin-converting enzyme inhibitors and angiotensin II–receptor antagonists are
recommended for patients with chronic kidney disease because these drugs can slow …

[HTML][HTML] A comparison of outcomes with angiotensin-converting–enzyme inhibitors and diuretics for hypertension in the elderly

LMH Wing, CM Reid, P Ryan, LJ Beilin… - … England Journal of …, 2003 - Mass Medical Soc
Background Treatment of hypertension with diuretics, beta-blockers, or both leads to
improved outcomes. It has been postulated that agents that inhibit the renin–angiotensin …

Use of angiotensin‐converting enzyme inhibitor therapy and dose‐related outcomes in older adults with new heart failure in the community

PA Rochon, K Sykora, SE Bronskill… - Journal of general …, 2004 - Wiley Online Library
OBJECTIVE: To evaluate the dose‐related benefit of angiotensin‐converting enzyme (ACE)
inhibitor therapy among older adults with heart failure and to evaluate whether low‐dose …

Combination angiotensin‐converting enzyme inhibitor and angiotensin receptor blocker therapy: its role in clinical practice

DA Sica - The Journal of Clinical Hypertension, 2003 - Wiley Online Library
Angiotensin‐converting enzyme inhibitors and angiotensin receptor blockers are commonly
prescribed for the management of hypertension. In addition, each of these drug classes has …

Efficacy and safety of angiotensin receptor blockers in older patients: a meta-analysis of randomized trials

IY Elgendy, T Huo, V Chik, CJ Pepine… - American journal of …, 2015 - academic.oup.com
BACKGROUND The efficacy and safety of angiotensin receptor blockers (ARBs) in the older
population is unclear. OBJECTIVES To determine the efficacy and safety of ARBs in older …

[HTML][HTML] An angiotensin II receptor blocker–calcium channel blocker combination prevents cardiovascular events in elderly high-risk hypertensive patients with chronic …

S Kim-Mitsuyama, H Ogawa, K Matsui, T Jinnouchi… - Kidney international, 2013 - Elsevier
The OSCAR study was a multicenter, prospective randomized open-label blinded end-point
study of 1164 Japanese elderly hypertensive patients comparing the efficacy of angiotensin …