A systematic review of cellular transplantation therapies for spinal cord injury

…, JS Sparling, JR Plemel, WT Plunet, EC Tsai… - Journal of …, 2011 - liebertpub.com
Cell transplantation therapies have become a major focus in pre-clinical research as a
promising strategy for the treatment of spinal cord injury (SCI). In this article, we systematically …

Matrix inclusion within synthetic hydrogel guidance channels improves specific supraspinal and local axonal regeneration after complete spinal cord transection

EC Tsai, PD Dalton, MS Shoichet, CH Tator - Biomaterials, 2006 - Elsevier
We have previously shown that a novel synthetic hydrogel channel composed of poly(2-hydroxyethyl
methacrylate-co-methyl methacrylate) (pHEMA-MMA) is biocompatible and …

Synthetic hydrogel guidance channels facilitate regeneration of adult rat brainstem motor axons after complete spinal cord transection

EC Tsai, PD Dalton, MS Shoichet… - Journal of neurotrauma, 2004 - liebertpub.com
Synthetic guidance channels or tubes have been shown to promote axonal regeneration within
the spinal cord from brainstem motor nuclei with the inclusion of agents such as matrices, …

[PDF][PDF] A cellular taxonomy of the adult human spinal cord

…, PF Mery, E Bourinet, L Bauchet, EC Tsai… - Neuron, 2023 - cell.com
The mammalian spinal cord functions as a community of cell types for sensory processing,
autonomic control, and movement. While animal models have advanced our understanding of …

The influence of time from injury to surgery on motor recovery and length of hospital stay in acute traumatic spinal cord injury: an observational Canadian cohort study

…, CS Rivers, H Ahn, J Paquet, EC Tsai… - Journal of …, 2015 - liebertpub.com
To determine the influence of time from injury to surgery on neurological recovery and length
of stay (LOS) in an observational cohort of individuals with traumatic spinal cord injury (tSCI)…

A clinical practice guideline for the management of patients with acute spinal cord injury and central cord syndrome: recommendations on the timing (≤ 24 hours …

…, K Palmieri, A Singh, AC Skelly, EC Tsai… - Global spine …, 2017 - journals.sagepub.com
Objective: To develop recommendations on the timing of surgical decompression in patients
with traumatic spinal cord injury (SCI) and central cord syndrome. Methods: A systematic …

A clinical practice guideline for the management of patients with acute spinal cord injury: recommendations on the use of methylprednisolone sodium succinate

…, K Palmieri, AC Skelly, A Singh, EC Tsai… - Global spine …, 2017 - journals.sagepub.com
Introduction: The objective of this guideline is to outline the appropriate use of methylprednisolone
sodium succinate (MPSS) in patients with acute spinal cord injury (SCI). Methods: A …

Sexual dimorphism in a neuronal mechanism of spinal hyperexcitability across rodent and human models of pathological pain

…, JA Landrigan, PJ Lombroso, Y De Koninck, EC Tsai… - Brain, 2022 - academic.oup.com
The prevalence and severity of many chronic pain syndromes differ across sex, and recent
studies have identified differences in immune signalling within spinal nociceptive circuits as a …

Loss of STEP61 couples disinhibition to N-methyl-d-aspartate receptor potentiation in rodent and human spinal pain processing

…, AG Godin, Y De Koninck, PJ Lombroso, EC Tsai… - Brain, 2019 - academic.oup.com
Dysregulated excitability within the spinal dorsal horn is a critical mediator of chronic pain.
In the rodent nerve injury model of neuropathic pain, BDNF-mediated loss of inhibition (…

Tumors of the skull base in children: review of tumor types and management strategies

EC Tsai, S Santoreneos, JT Rutka - Neurosurgical Focus, 2002 - thejns.org
Although many treatment strategies for skull base tumors in adults have been reported, relatively
little has been reported regarding such therapies in the pediatric population. Skull base …