Traumatic brain injury: can the consequences be stopped?

E Park, JD Bell, AJ Baker - Cmaj, 2008 - Can Med Assoc
Traumatic brain injury is a leading cause of morbidity and death in both industrialized and
developing countries. To date, there is no targeted pharmacological treatment that effectively …

Neuroprotection for traumatic brain injury

DJ Loane, BA Stoica, AI Faden - Handbook of clinical neurology, 2015 - Elsevier
Traumatic brain injury (TBI) is a major cause of mortality and morbidity worldwide. Despite
extensive preclinical research supporting the effectiveness of neuroprotective therapies for …

Pathophysiology of severe traumatic brain injury.

RA O'leary, AD Nichol - Journal of neurosurgical sciences, 2018 - europepmc.org
Traumatic brain injury is a leading cause of morbidity and mortality globally, particularly
among young people, with significant social and economic effects. The World Health …

[HTML][HTML] Traumatic brain injuries: pathophysiology and potential therapeutic targets

SY Ng, AYW Lee - Frontiers in cellular neuroscience, 2019 - frontiersin.org
Traumatic brain injury (TBI) remains one of the leading causes of morbidity and mortality
amongst civilians and military personnel globally. Despite advances in our knowledge of the …

[HTML][HTML] Neuroprotective strategies for traumatic brain injury: improving clinical translation

SV Kabadi, AI Faden - International journal of molecular sciences, 2014 - mdpi.com
Traumatic brain injury (TBI) induces secondary biochemical changes that contribute to
delayed neuroinflammation, neuronal cell death, and neurological dysfunction. Attenuating …

[HTML][HTML] Revisiting traumatic brain injury: from molecular mechanisms to therapeutic interventions

A Jarrahi, M Braun, M Ahluwalia, RV Gupta, M Wilson… - Biomedicines, 2020 - mdpi.com
Studying the complex molecular mechanisms involved in traumatic brain injury (TBI) is
crucial for developing new therapies for TBI. Current treatments for TBI are primarily focused …

Pathophysiology of traumatic brain injury

MW Greve, BJ Zink - Mount Sinai Journal of Medicine: A …, 2009 - Wiley Online Library
Traumatic brain injury is a major source of death and disability worldwide. Significant
success has been achieved in improving short‐term outcomes in severe traumatic brain …

[HTML][HTML] White matter damage after traumatic brain injury: a role for damage associated molecular patterns

M Braun, K Vaibhav, NM Saad, S Fatima… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Traumatic brain injury (TBI) is a leading cause of mortality and long-term morbidity
worldwide. Despite decades of pre-clinical investigation, therapeutic strategies focused on …

Pathophysiology associated with traumatic brain injury: current treatments and potential novel therapeutics

ML Pearn, IR Niesman, J Egawa, A Sawada… - Cellular and molecular …, 2017 - Springer
Traumatic brain injury (TBI) is one of the leading causes of death of young people in the
developed world. In the United States alone, 1.7 million traumatic events occur annually …

[HTML][HTML] Emerging therapies in traumatic brain injury

PM Kochanek, TC Jackson, NM Ferguson… - Seminars in …, 2015 - thieme-connect.com
Despite decades of basic and clinical research, treatments to improve outcomes after
traumatic brain injury (TBI) are limited. However, based on the recent recognition of the …