Optical mapping of Langendorff-perfused human hearts: establishing a model for the study of ventricular fibrillation in humans

…, V Rao, S Mironov, E Sevaptsidis… - American Journal …, 2007 - journals.physiology.org
Our objective was to establish a novel model for the study of ventricular fibrillation (VF) in
humans. We adopted the established techniques of optical mapping to human ventricles for the …

Ventricular fibrillation in myopathic human hearts: mechanistic insights from in vivo global endocardial and epicardial mapping

…, E Downar, V Chauhan, E Sevaptsidis… - American Journal …, 2007 - journals.physiology.org
Ventricular fibrillation (VF) is an important cause of sudden cardiac death and cardiovascular
mortality in patients with cardiomyopathy. Although it was generally believed that chaotic …

Ventricular tachycardia after surgical repair of tetralogy of Fallot: results of intraoperative mapping studies

…, L Mickleborough, W Williams, E Sevaptsidis… - Journal of the American …, 1992 - Elsevier
Objectives. Four patients with previous repair of tetralogy of Fallot and ventricular tachycardia
underwent map-guided surgery to ablate the arrhythmias. Background. Although patients …

Cardiac electrophysiological consequences of neuromuscular incapacitating device discharges

…, VS Chauhan, E Downar, E Sevaptsidis - Journal of the American …, 2006 - jacc.org
Objectives : The purpose of this study was to evaluate the cardiac consequences of
neuromuscular incapacitating device (NID)/stun gun discharge in an experimental model. …

Endocardial mapping of ventricular tachycardia in the intact human heart. II. Evidence for multiuse reentry in a functional sheet of surviving myocardium

…, L Harris, L Mickleborough, E Sevaptsidis… - Journal of the American …, 1992 - Elsevier
Objective.The purpose of this study was to obtain improved detection and characterization of
reentrant circuits in the n-farcted human ventricle. Background. The return path of reentrant …

Cardiac stimulation with high voltage discharge from stun guns

…, S Massé, K Umapathy, P Dorian, E Sevaptsidis… - Cmaj, 2008 - Can Med Assoc
The ability of an electrical discharge to stimulate the heart depends on the duration of the
pulse, the voltage and the current density that reaches the heart. Stun guns deliver very short …

Endocardial mapping of ventricular tachycardia in the intact human ventricle. III. Evidence of multiuse reentry with spontaneous and induced block in portions of …

…, J Saito, JC Doig, TCK Chen, E Sevaptsidis… - Journal of the American …, 1995 - Elsevier
Objectives. This study was conducted to characterized the functional nature of the reentrant
tract responsible for ventricular tachycardia due to ischemic heart disease. Background. A …

Electrogram fractionation in murine HL-1 atrial monolayer model

…, M Husain, T Farid, E Downar, E Sevaptsidis… - Heart Rhythm, 2008 - Elsevier
BACKGROUND: Complex fractionated atrial electrograms have been suggested as important
targets for catheter ablation of atrial fibrillation. The etiology and the mechanism of these …

Effect of global ischemia and reperfusion during ventricular fibrillation in myopathic human hearts

…, J Asta, H Ross, V Rao, E Sevaptsidis… - American Journal …, 2009 - journals.physiology.org
The effect of lack of global coronary perfusion on myocardial activation rate, wavebreak, and
its temporal progression during human ventricular fibrillation (VF) is not known. We tested …

Spatiotemporal frequency analysis of ventricular fibrillation in explanted human hearts

K Umapathy, S Masse, E Sevaptsidis… - IEEE Transactions …, 2008 - ieeexplore.ieee.org
Ventricular fibrillation (VF) is a medical condition that occurs due to rapid and irregular electrical
activity of heart. If undiagnosed or untreated, VF leads to sudden cardiac death. VF has …