User profiles for Duminda N. Wijeysundera

Duminda N. Wijeysundera

Professor of Anesthesiology and Pain Medicine, University of Toronto
Verified email at utoronto.ca
Cited by 41486

Assessment of functional capacity before major non-cardiac surgery: an international, prospective cohort study

DN Wijeysundera, RM Pearse, MA Shulman… - The Lancet, 2018 - thelancet.com
Background Functional capacity is an important component of risk assessment for major
surgery. Doctors' clinical subjective assessment of patients' functional capacity has uncertain …

Alpha-2 adrenergic agonists to prevent perioperative cardiovascular complications:: A meta-analysis

DN Wijeysundera, JS Naik, WS Beattie - The American journal of medicine, 2003 - Elsevier
PURPOSE: To investigate the effects of α 2 -adrenergic agonists on perioperative mortality
and cardiovascular complications in adults undergoing surgery. METHODS: MEDLINE (1966 …

2014 ACC/AHA guideline on perioperative cardiovascular evaluation and management of patients undergoing noncardiac surgery: a report of the American College …

…, HH Ting, BF Uretsky, DN Wijeysundera - Journal of the American …, 2014 - jacc.org
The recommendations listed in this CPG are, whenever possible, evidence based. In April
2013, an extensive evidence review was conducted, which included a literature review …

Derivation and validation of a simplified predictive index for renal replacement therapy after cardiac surgery

DN Wijeysundera, K Karkouti, JY Dupuis, V Rao… - Jama, 2007 - jamanetwork.com
ContextA predictive index for renal replacement therapy (RRT; hemodialysis or continuous
venovenous hemodiafiltration) after cardiac surgery may improve clinical decision making …

Epidural anaesthesia and survival after intermediate-to-high risk non-cardiac surgery: a population-based cohort study

DN Wijeysundera, WS Beattie, PC Austin, JE Hux… - The Lancet, 2008 - thelancet.com
Background Although epidural anaesthesia and analgesia have numerous benefits, their
effects on postoperative survival are unclear. We therefore undertook a population-based …

Association of intraoperative hypotension with acute kidney injury after elective noncardiac surgery

LY Sun, DN Wijeysundera, GA Tait, WS Beattie - Anesthesiology, 2015 - pubs.asahq.org
Background: Intraoperative hypotension (IOH) may be associated with postoperative acute
kidney injury (AKI), but the duration of hypotension for triggering harm is unclear. The authors …

Risk of elective major noncardiac surgery after coronary stent insertion: a population-based study

DN Wijeysundera, HC Wijeysundera, L Yun… - Circulation, 2012 - Am Heart Assoc
Background— Guidelines recommend that noncardiac surgery be delayed until 30 to 45
days after bare-metal stent implantation and 1 year after drug-eluting stent implantation. …

Off-pump coronary artery surgery for reducing mortality and morbidity: meta-analysis of randomized and observational studies

DN Wijeysundera, WS Beattie, G Djaiani, V Rao… - Journal of the American …, 2005 - jacc.org
Objectives : The purpose of this study was to assess the effects of off-pump coronary bypass
surgery (OPCAB) on mortality and morbidity. Background : Despite its potential for reducing …

Perioperative beta blockade in noncardiac surgery: a systematic review for the 2014 ACC/AHA guideline on perioperative cardiovascular evaluation and management …

DN Wijeysundera, D Duncan, C Nkonde-Price… - Circulation, 2014 - Am Heart Assoc
Objective— To review the literature systematically to determine whether initiation of beta
blockade within 45 days prior to noncardiac surgery reduces 30-day cardiovascular morbidity …

Rates and risk factors for prolonged opioid use after major surgery: population based cohort study

H Clarke, N Soneji, DT Ko, L Yun, DN Wijeysundera - Bmj, 2014 - bmj.com
Objective To describe rates and risk factors for prolonged postoperative use of opioids in
patients who had not previously used opioids and undergoing major elective surgery. Design …