Background: Hyperglycemia is associated with increased mortality in critically ill patients.
Randomized trials of intensive insulin therapy have reported inconsistent effects on mortality …

Background Hyperglycemia is common in critically ill hospitalized patients, and it is
associated with adverse outcomes, including increased mortality. The objective of this meta …

Background: Hyperglycemia is common in critically ill hospitalized patients and has been
associated with adverse outcomes, including increased mortality. In this review, we examine …

Objective: The role of intensive insulin therapy in medical surgical intensive care patients
remains unclear. The objective of this study was to examine the effect of intensive insulin …

Intensive insulin therapy (IIT) improves the outcome of prolonged critically ill patients, but
concerns remain regarding potential harm and the optimal blood glucose level. These …

Objectives: To examine the predisposing factors for hypoglycemia in medical-surgical
intensive care unit patients treated with intensive insulin therapy and to assess its …

Background Following publication of the Leuven Intensive Insulin Therapy Trial in 2001,
tight glycemic control became the standard of care in ICUs around the world. Recent studies …

Context: Hyper-and hypoglycemia are associated with increased mortality of critically ill
patients, but whether this association is causal remains unclear. Early randomized …

OBJECTIVE: To evaluate the clinical outcomes of glycemic control of intensive insulin
therapy and recommend its place in the management of critically ill patients. DATA …

Background: The benefits and harms of intensive insulin therapy (IIT) titrated to strict
glycemic targets in hospitalized patients remain uncertain. Purpose: To evaluate the benefits …