The excellent meta-analysis by Ryan Zarychanski and associates demonstrated that the use
of erythropoietinreceptor agonists in critically ill patients does not improve clinically …

Introduction: Anemia and the need for red blood cell transfusions are common among
patients admitted to intensive care units. Erythropoietin has been used to decrease the need …

Dear Editor, We read with great interest the clinical practice guidelines on transfusion
strategies recently published in the journal [1]. Although it followed a well designed and …

Inflammation plays a major pathological role in spinal cord injury (SCI). Although
antiinflammatory treatment using the glucocorticoid methyprednisolone sodium succinate …

There are currently no effective means to treat acute spinal cord injury, except for
glucocorticoids, which produce moderate benefits at best. A new study suggests …

We read with interest Lasocki et al.'s letter [1]. We agree with many points, especially their
call for further research into the clinical effects of erythropoietin (EPO) in critically ill patients …

Critical Care and Resuscitation• Volume 10 Number 3• September 2008 258 have acute
renal failure (the low–normal range). Interestingly, these levels are not substantially different …

Acute lesions of the spinal cord lead to dramatic changes in neuronal function. In the present
study, we examined the possible involvement of neurotrophic factors in the action of the drug …

Objective To describe off-label utilization of erythropoietic agents in ICU patients. Methods A
retrospective, observational study design was used to describe off-label utilization of …

Purpose Severe immune dysregulation is common in patients admitted to the intensive care
unit (ICU) and is associated with adverse outcomes. Erythropoietin-stimulating agents …