Objective: To systematically review the benefits and risks associated with the use of
benzodiazepines to treat insomnia in adults. Data sources: MEDLINE and the Cochrane Controlled …

OBJECTIVE: To analyse the evidence for the efficacy and potential harmful effects of
benzodiazepines compared with other therapies in the treatment of acute alcohol withdrawal. DATA …

INSOMNIA, OR THE DISSATISFACTION WITH THE QUANTITY, quality or timing of sleep, is
a common complaint. Because the definition of "normal" sleep is not well established, the …

Background The prevalence of type II diabetes among individuals suffering from schizophrenia
or schizoaffective disorders is more than double that of the general population. By 2005, …

"Gamified" active learning has been shown to increase students' academic performance and
engagement and help them make more social connections than standard course settings. …

The process of nucleocytoplasmic shuttling is mediated by karyopherins. Dysregulated
expression of karyopherins may trigger oncogenesis through aberrant distribution of cargo …

Background Posttraumatic stress disorder acquired at work can be debilitating both for workers
and their employers. The disorder can result in increased sick leave, reduced productivity…

Background Evidence from Ontario and globally has associated pandemic-related stay-at-home
orders, closures of schools and recreation with increased screen time for children and …

Alcohol abuse produces a considerable burden of illness in the Canadian population. The
diagnosis of alcohol dependence and withdrawal can be difficult, particularly in the setting of …

Intracellular reactive oxygen species (ROS) may participate in cellular responses to various
stimuli including hemodynamic forces and act as signal transduction messengers. Human …