In today's Lancet, the INTERHEART study investigators report a well-coordinated study of
risk factors for myocardial infarction in multiple populations. They present hazard ratios and …

Comment of 20 items (table). The WHO-mandated items collectively address every key
requirement that we established in our September, 2004, editorial. The ICMJE supports the …

THE LANCET• Vol 363• May 22, 2004• www. thelancet. com 1729 based on expected
prognosis, with the intention to change a disease outcome. Judgment of a patient's …

13 Intervention (s) Specific name of intervention (s) and comparator/control (s). Use
International Non-Proprietary Name if possible (not brand/trade names). For unregistered …

Comment 1910 www. thelancet. com Vol 369 June 9, 2007 require registration, and the
registration of trial results. As is always the case, the ICMJE establishes policy only for the 12 …

May 20, 2005, saw the first ever international clinical trials day, 1 celebrating the contribution
of James Lind2 to the concept of medical research and recognising that biomedical research …

Clinical trial registration has been a popular topic in the past 12 months. WHO, 1 the
pharmaceutical industry, 2 several national research institutions, 3 and independent …

For personal use. Only reproduce with permission from The Lancet Publishing Group.
scientific quality, as well as the humanistic relevance, of patient-oriented research cannot be …

The protocol is an important document that details the background, methods, ethical
considerations, and administration of a clinical trial. 1 The information contained in the …

Clinical trials may lead to conflicting results. We studied how different ways of reporting
results affected physicians' recommendations. A questionnaire distributed to 148 general …