User profiles for Caroline Sirois

Caroline Sirois

Professeur titulaire, Faculté de Pharmacie, Université Laval
Verified email at pha.ulaval.ca
Cited by 2066

Potentially inappropriate medications in older adults: a population-based cohort study

B Roux, C Sirois, M Simard, ME Gagnon… - Family …, 2020 - academic.oup.com
Background Non-optimal medication use among older adults is a public health concern. A
concrete picture of potentially inappropriate medication (PIM) use is imperative to ensure …

Validation of the combined comorbidity index of Charlson and Elixhauser to predict 30-day mortality across ICD-9 and ICD-10

M Simard, C Sirois, B Candas - Medical care, 2018 - journals.lww.com
Objectives: To validate and compare performance of an International Classification of Diseases,
tenth revision (ICD-10) version of a combined comorbidity index merging conditions of …

Community-dwelling older people's attitudes towards deprescribing in Canada

C Sirois, N Ouellet, E Reeve - Research in Social and Administrative …, 2017 - Elsevier
Background While there is evidence that supervised withdrawal of inappropriate medications
might be beneficial for individuals with polypharmacy, little is known about their attitudes …

Exploring polypharmacy with artificial intelligence: data analysis protocol

C Sirois, R Khoury, A Durand, PL Deziel… - BMC Medical Informatics …, 2021 - Springer
Background Polypharmacy is common among older adults and it represents a public health
concern, due to the negative health impacts potentially associated with the use of several …

Association between nutrition and the evolution of multimorbidity: the importance of fruits and vegetables and whole grain products

G Ruel, Z Shi, S Zhen, H Zuo, E Kröger, C Sirois… - Clinical Nutrition, 2014 - Elsevier
Background & aims Multimorbidity is a common health status. The impact of nutrition on the
development of multimorbidity remains to be determined. The aim of this study is to …

Polypharmacy definitions for multimorbid older adults need stronger foundations to guide research, clinical practice and public health

C Sirois, NS Domingues, ML Laroche, A Zongo… - Pharmacy, 2019 - mdpi.com
There are numerous definitions of polypharmacy to describe the use of many medications
among older adults, but there is a need to clarify if they are purposive and meaningful. By …

Effect of gender, sex hormones, time variables and physiological urinary pH on apparent CYP2D6 activity as assessed by metabolic ratios of marker substrates

L Labbé, C Sirois, S Pilote, M Arseneault… - Pharmacogenetics …, 2000 - journals.lww.com
The effects of gender, time variables, menstrual cycle phases, plasma sex hormone concentrations
and physiologic urinary pH on CYP2D6 phenotyping were studied using two widely …

Efficacy of school-based interventions aimed at decreasing sugar-sweetened beverage consumption among adolescents: a systematic review

…, A Bélanger-Gravel, D Boucher, C Sirois… - Public health …, 2017 - cambridge.org
Objective To verify the efficacy of school-based interventions aimed at reducing sugar-sweetened
beverage (SSB) consumption among adolescents in order to develop or improve …

A new care model reduces polypharmacy and potentially inappropriate medications in long-term care

…, E Kröger, PH Carmichael, R Rouleau, C Sirois - Journal of the American …, 2021 - Elsevier
… panel Carolina Tisnado Garland BScN a b , Line Guénette PhD c d , Edeltraut Kröger PhD
b c , Pierre-Hugues Carmichael MSc b , Rachel Rouleau MSc e f , Caroline Sirois PhD a b …

Is benzodiazepine use associated with the risk of dementia and cognitive impairment–not dementia in older persons? The Canadian study of health and aging

M Nafti, C Sirois, E Kröger… - Annals of …, 2020 - journals.sagepub.com
Background: The use of benzodiazepines in relation to cognitive decline remains an area of
controversy in aging populations. Objective: This study aims to evaluate the risk of cognitive …