Cardiac complications in 110 patients (mean age, 32.5 ± 11.4 years) with thalassemia
intermedia (TI) were studied. Sixty-seven (60.9%) of them had not been transfused or were …

BACKGROUND: Women with polycystic ovary syndrome (PCOS) have an increased
prevalence of insulin resistance (IR) and related disorders. Elevated serum levels of cellular …

Background Heart disease represents the main determinant of survival in β-thalassemia, but
its particular features in the two clinical forms of the disease, thalassemia major (TM) and …

β-Thalassemia is an inherited hemoglobin disorder resulting in chronic hemolytic anemia
that typically requires life-long transfusion therapy. Although traditionally prevalent in the …

Objective: To assess cardiac status in a large group of patients with thalassemia major who
had been treated in a standard way since their early infancy with intensive transfusions and …

Infectious complications constitute the second most common cause of mortality and a main
cause of morbidity in β-thalassemia. Besides the high risk of blood-borne infections …

Heart disease is the leading cause of mortality and one of the main causes of morbidity in β-thalassemia.
The clinical spectrum of the thalassemia syndrome ranges from the severe, …

The development of clinical and histopathologic manifestations of a diffuse elastic tissue
defect, resembling inherited pseudoxanthoma elasticum (PXE), has been encountered with a …

Hemoglobinopathies constitute a heterogeneous group of hereditary hemoglobin disorders
characterized by either reduced (thalassemias) or defective (sickle cell disease) globin chain …

Cardiac involvement represents the leading cause of mortality in both forms of β‐thalassemia,
namely, thalassemia major (TM) and thalassemia intermedia (TI), and pulmonary …