Annexins in Cell Membrane Dynamics: Ca2+-Regulated Association of Lipid Microdomains

EB Babiychuk, A Draeger - The Journal of cell biology, 2000 - rupress.org
The sarcolemma of smooth muscle cells is composed of alternating stiff actin-binding, and
flexible caveolar domains. In addition to these stable macrodomains, the plasma membrane …

Plasma membrane repair and cellular damage control: the annexin survival kit

A Draeger, K Monastyrskaya, EB Babiychuk - Biochemical pharmacology, 2011 - Elsevier
Plasmalemmal injury is a frequent event in the life of a cell. Physical disruption of the plasma
membrane is common in cells that operate under conditions of mechanical stress. The …

Engineered liposomes sequester bacterial exotoxins and protect from severe invasive infections in mice

…, A Scherag, E Gulbins, A Kadioglu, A Draeger… - Nature …, 2015 - nature.com
Gram-positive bacterial pathogens that secrete cytotoxic pore-forming toxins, such as
Staphylococcus aureus and Streptococcus pneumoniae, cause a substantial burden of disease. …

Association between statin-associated myopathy and skeletal muscle damage

…, L Iyer, H Hoppeler, F Breil, A Draeger - Cmaj, 2009 - Can Med Assoc
Background: Many patients taking statins often complain of muscle pain and weakness. The
extent to which muscle pain reflects muscle injury is unknown. Methods: We obtained …

Improved isolation strategies to increase the yield and purity of human urinary exosomes for biomarker discovery

…, M Vögeli, U Baumgartner, E Vassella, A Draeger… - Scientific reports, 2018 - nature.com
Circulating miRNAs are detected in extracellular space and body fluids such as urine.
Circulating RNAs can be packaged in secreted urinary extracellular vesicles (uEVs) and thus …

Blebbing confers resistance against cell lysis

…, K Monastyrskaya, S Potez, A Draeger - Cell Death & …, 2011 - nature.com
The plasma membrane constitutes a barrier that maintains the essential differences between
the cytosol and the extracellular environment. Plasmalemmal injury is a common event …

Statin therapy induces ultrastructural damage in skeletal muscle in patients without myalgia

A Draeger, K Monastyrskaya… - The Journal of …, 2006 - Wiley Online Library
Muscle pain and weakness are frequent complaints in patients receiving 3‐hydroxymethylglutaryl
coenzymeA (HMG CoA) reductase inhibitors (statins). Many patients with myalgia …

The annexins: spatial and temporal coordination of signaling events during cellular stress

K Monastyrskaya, EB Babiychuk, A Draeger - Cellular and molecular life …, 2009 - Springer
Annexins are a family of structurally related, Ca 2+ -sensitive proteins that bind to negatively
charged phospholipids and establish specific interactions with other lipids and lipid …

[HTML][HTML] MicroRNAs may mediate the down-regulation of neurokinin-1 receptor in chronic bladder pain syndrome

…, FC Burkhard, TM Kessler, A Kuhn, A Draeger… - The American journal of …, 2010 - Elsevier
Bladder pain syndrome (BPS) is a clinical syndrome of pelvic pain and urinary urgency-frequency
in the absence of a specific cause. Investigating the expression levels of genes …

Increased cholesterol decreases uterine activity: functional effects of cholesterol alteration in pregnant rat myometrium

…, EB Babiychuk, K Noble, A Draeger… - American Journal of …, 2005 - journals.physiology.org
Uterine quiescence is essential for successful pregnancy. Cholesterol and triglycerides are
markedly increased in pregnancy. Cholesterol is enriched in microdomains of the plasma …