User profiles for Andrew Leung

Andrew Leung

Netflix
Verified email at soe.ucsc.edu
Cited by 1337

Energy landscapes of receptor–ligand bonds explored with dynamic force spectroscopy

R Merkel, P Nassoy, A Leung, K Ritchie, E Evans - Nature, 1999 - nature.com
Atomic force microscopy (AFM) 1 , 2 has been used to measure the strength of bonds
between biological receptor molecules and their ligands 3 , 4 , 5 , 6 . But for weak noncovalent …

[BOOK][B] Dynamic stiffness and substructures

AYT Leung - 2012 - books.google.com
… AYT Leung 1985. Dynamic stiffness method for exponentially varying harmonic excitation of
… J Sound Vib 106, 145–151 AYT Leung 1987. A simple method for exponentially modulated …

Particle swarm optimization of tuned mass dampers

AYT Leung, H Zhang - Engineering Structures, 2009 - Elsevier
Tuned mass dampers (TMD) have been widely used to attenuate undesirable vibrations in
engineering. Most optimization problems of TMD are solved by either numerical iteration …

[BOOK][B] Bifurcation and chaos in engineering

Y Chen, AYT Leung - 2012 - books.google.com
For the many different deterministic non-linear dynamic systems (physical, mechanical,
technical, chemical, ecological, economic, and civil and structural engineering), the discovery of …

Mechanical switching and coupling between two dissociation pathways in a P-selectin adhesion bond

E Evans, A Leung, V Heinrich… - Proceedings of the …, 2004 - National Acad Sciences
Many biomolecular bonds exhibit a mechanical strength that increases in proportion to the
logarithm of the rate of force application. Consistent with exponential decrease in bond …

Particle swarm optimization of TMD by non‐stationary base excitation during earthquake

AYT Leung, H Zhang, CC Cheng… - … Engineering & Structural …, 2008 - Wiley Online Library
There are many traditional methods to find the optimum parameters of a tuned mass
damper (TMD) subject to stationary base excitations. It is very difficult to obtain the optimum …

Single exposure to heat induces stage-specific germ cell apoptosis in rats: role of intratesticular testosterone on stage specificity

…, RS Swerdloff, P Im, KS Taing, T Bui, A Leung… - …, 1999 - academic.oup.com
Short term exposure of the testis to heat causes degeneration of germ cells. However, the
mechanisms underlying this process are poorly understood. The major objectives of this study …

Measurement and analysis of {Large-Scale} network file system workloads

AW Leung, S Pasupathy, G Goodson… - 2008 USENIX Annual …, 2008 - usenix.org
In this paper we present the analysis of two large-scale network file system workloads. We
measured CIFS traffic for two enterprise-class file servers deployed in the NetApp data center …

Chemically distinct transition states govern rapid dissociation of single L-selectin bonds under force

E Evans, A Leung, D Hammer… - Proceedings of the …, 2001 - National Acad Sciences
Carbohydrate–protein bonds interrupt the rapid flow of leukocytes in the circulation by
initiation of rolling and tethering at vessel walls. The cell surface carbohydrate ligands are …

Rados: a scalable, reliable storage service for petabyte-scale storage clusters

SA Weil, AW Leung, SA Brandt… - Proceedings of the 2nd …, 2007 - dl.acm.org
Brick and object-based storage architectures have emerged as a means of improving the
scalability of storage clusters. However, existing systems continue to treat storage nodes as …