Fundamental problem with opioid trials for chronic pain

AD Furlan, A Mailis-Gagnon, E Tunks - CMAJ, 2007 - Can Med Assoc
Allan Detsky's timely editorial1 invites us to take a broader look at the biases that shape the
recommendations in clinical practice guidelines, beyond financial links with the …

Response to “Opioids for chronic pain”

JW Busse, D Juurlink, DN Buckley, GH Guyatt - CMAJ, 2019 - Can Med Assoc
In his letter to CMAJ, Mr. Ross has engaged in selective citation to support his position that
opioids are highly effective for chronic noncancer pain and that development of opioid use …

[HTML][HTML] The authors respond to “inconsistencies in the 2017 Canadian guideline for opioids for chronic noncancer pain”

JW Busse, DN Juurlink, DN Buckley, GH Guyatt - CMAJ, 2017 - Can Med Assoc
We value Drs. Weinberg's and Baer's careful review and feedback1 on the 2017 Canadian
Guideline for Opioid Therapy and Chronic Noncancer Pain, 2 and we would like to respond …

[HTML][HTML] Drivers of the opioid crisis: an appraisal of financial conflicts of interest in clinical practice guideline panels at the peak of opioid prescribing

S Spithoff, P Leece, F Sullivan, N Persaud, P Belesiotis… - PloS one, 2020 - journals.plos.org
Background Starting in the late 1990s, the pharmaceutical industry sought to increase
prescribing of opioids for chronic non-cancer pain. Influencing the content of clinical practice …

Grading of Recommendations Assessment, Development and Evaluation (GRADE) clinical evidence review ratings of the evidence for the key clinical questions1 in …

D Dowell, KR Ragan, CM Jones, GT Baldwin, R Chou - 2022 - stacks.cdc.gov
Clinical Practice Guidelines Grade Tables Page 1 G-1 Grading of Recommendations
Assessment, Development and Evaluation (GRADE) clinical evidence review ratings of the …

Opioid deprescribing guidelines and consumer preferences: betwixt and between

MD Sullivan - Pain, 2021 - journals.lww.com
The qualitative study by Langford and colleagues,“The lesser of 2 evils”: a framework
analysis of consumers' perspectives on opioid deprescribing and the development of opioid …

Unintended harm from opioid prescribing guidelines

SM Fishman, LR Webster - Pain Medicine, 2009 - academic.oup.com
There is a new front in the ongoing battle to preserve access to pain relief, and a Trojan
horse is nestled inside a measure intended to protect patients from harm. It takes the form of …

[HTML][HTML] Pain management, prescription opioid mortality, and the CDC: is the devil in the data?

ME Schatman, SJ Ziegler - Journal of pain research, 2017 - Taylor & Francis
Transparency, freedom from bias, and accountability are, in principle, hallmarks of taxpayer-
funded institutions. Unfortunately, it seems that at least one institution, the Centers for …

[PDF][PDF] CDC Guidelines on Prescription of Opioids–More and Less Than Meets the Eye. Nur Primary Care. 2022; 6 (5): 1-6

RA Lawhern - Co-Founder, Alliance for the Treatment of Intractable … - scivisionpub.com
ABSTRACT On February 10, 2022, the US Centers For Disease Control and Prevention
(National Center for Injury Prevention and Control) circulated a draft revised and expanded …

A meta-analysis based on diffuse definitions and mixed quality literature is not a good fundament for decisions on treatment of chronic pain patients

W Scholten, JE Henningfield - Pain, 2015 - journals.lww.com
Vowles et al. 6 provide definitions for misuse, abuse, and addiction, which deviate from what
is generally understood by these terms. This creates confusion and is a potential source for …