Background—The natural histories of equally severe symptomatic and asymptomatic carotid
stenoses are very different, which suggests dichotomy in plaque behavior. The vascular …

Background Venous disease is the most common cause of leg ulceration. Although
compression therapy improves venous ulcer healing, it does not treat the underlying causes of …

Purpose: This prospective study aimed to validate a newly designed specific measure of
quality of life for patients with venous ulcers. Methods: The study was set in a London teaching …

… In the 1960s, transient ischaemic attacks were considered to be sudden, focal
neurological deficits of vascular origin lasting less than 24 h (an arbitrarily assigned …

Aims We sought to determine whether intraplaque inflammation could be measured with
positron emission tomography/computed tomography angiography (PET/CTA) using 11 C-…

Chronic venous disease (CVD) is a prevalent condition that tends to worsen with age. Patients
initially seek treatment to relieve symptoms of leg pain, discomfort, heaviness and swelling…

Background— We sought to perform a systematic lipid analysis of atherosclerotic plaques
using emerging mass spectrometry techniques. Methods and Results— A chip-based robotic …

… The members of the Guideline Development Group were Alun Davies (chair), professor of
vascular surgery, Imperial College London, and consultant vascular surgeon, Imperial College …

CME cations. Poorly fitting stockings can cause discomfort and, at worst, pressure necrosis.
The use of graduated compression stockings on legs with impaired arterial flow can worsen …

Background— Inflammation and matrix degradation are the hallmarks of high-risk atherosclerosis
that leads to myocardial infarction and stroke. Toll-like receptors (TLRs), key players in …