[HTML][HTML] Rational use of tocilizumab in the treatment of novel coronavirus pneumonia
S Zhang, L Li, A Shen, Y Chen, Z Qi - Clinical drug investigation, 2020 - Springer
Since December 2019, a novel coronavirus pneumonia (COVID-19) has broken out in Wuhan,
China and spread rapidly. Recent studies have found that ⁓ 15.7% of patients develop …
China and spread rapidly. Recent studies have found that ⁓ 15.7% of patients develop …
Advances in anti-breast cancer drugs and the application of nano-drug delivery systems in breast cancer therapy
X Fang, J Cao, A Shen - Journal of Drug Delivery Science and Technology, 2020 - Elsevier
Breast cancer is one of the most common malignant tumors among women. Although the
traditional breast cancer therapies are effective, there have numerous shortcomings, including …
traditional breast cancer therapies are effective, there have numerous shortcomings, including …
Advances and challenges in deep generative models for de novo molecule generation
…, Z Yang, G Chuai, S Qu, A Shen… - Wiley …, 2019 - Wiley Online Library
The de novo molecule generation problem involves generating novel or modified molecular
structures with desirable properties. Taking advantage of the great representation learning …
structures with desirable properties. Taking advantage of the great representation learning …
Oxygen self‐supply engineering‐ferritin for the relief of hypoxia in tumors and the enhancement of photodynamic therapy efficacy
…, D Jin, M Liu, Y Dai, L Li, X Zheng, L Wang, A Shen… - Small, 2022 - Wiley Online Library
Hypoxia is a hallmark of the tumor microenvironment (TME) that promotes tumor development
and metastasis. Photodynamic therapy (PDT) is a promising strategy in the treatment of …
and metastasis. Photodynamic therapy (PDT) is a promising strategy in the treatment of …
Nitric‐Oxide‐Releasing aza‐BODIPY: A New Near‐Infrared J‐Aggregate with Multiple Antibacterial Modalities
X Bao, S Zheng, L Zhang, A Shen, G Zhang… - Angewandte …, 2022 - Wiley Online Library
The development of near‐infrared (NIR) J‐aggregates has received increasing attention
due to their broad applications. Here, we report the nitrosation of an amine‐containing aza‐…
due to their broad applications. Here, we report the nitrosation of an amine‐containing aza‐…
[HTML][HTML] Risk factors on admission associated with hospital length of stay in patients with COVID-19: a retrospective cohort study
…, Z Kuang, Y Luo, T Yang, J Xu, J Yu, C Wen, A Shen - Scientific Reports, 2021 - nature.com
Treating patients with COVID-19 is expensive, thus it is essential to identify factors on admission
associated with hospital length of stay (LOS) and provide a risk assessment for clinical …
associated with hospital length of stay (LOS) and provide a risk assessment for clinical …
[HTML][HTML] The lncRNA-GAS5/miR-221-3p/DKK2 axis modulates ABCB1-mediated adriamycin resistance of breast cancer via the Wnt/β-catenin signaling pathway
…, T Pan, D Jiang, L Jin, Y Geng, X Feng, A Shen… - … Therapy-Nucleic Acids, 2020 - cell.com
Drug resistance, including adriamycin (ADR)-based therapeutic resistance, is a crucial cause
of chemotherapy failure in breast cancer treatment. Acquired chemoresistance has been …
of chemotherapy failure in breast cancer treatment. Acquired chemoresistance has been …
[HTML][HTML] Novel coronavirus (SARS-CoV-2) infection in a renal transplant recipient: case report
…, Z Yao, S Zhang, D Zhao, B Nashan, A Shen… - American journal of …, 2020 - Elsevier
An ongoing outbreak of pneumonia associated with the severe acute respiratory coronavirus
2 (SARS-CoV-2) started in Wuhan, China, with cases now confirmed in multiple countries. …
2 (SARS-CoV-2) started in Wuhan, China, with cases now confirmed in multiple countries. …
The short-term effects of air pollutants on hospitalizations for respiratory disease in Hefei, China
J Xie, J Teng, Y Fan, R Xie, A Shen - International journal of …, 2019 - Springer
Previous studies have shown that ambient air pollution is associated with respiratory morbidity.
However, the effects of air pollutants on health have rarely been studied in China. Our …
However, the effects of air pollutants on health have rarely been studied in China. Our …
[HTML][HTML] Treatment of patients with nonsevere and severe coronavirus disease 2019: an evidence-based guideline
…, RA Fowler, H Qiu, L Wei, L Sang, M Loeb, N Shen… - Cmaj, 2020 - Can Med Assoc
2019 (COVID-19) is either indirect (from studies of influenza, severe acute respiratory
syndrome and Middle East respiratory syndrome) or from several observational studies and …
syndrome and Middle East respiratory syndrome) or from several observational studies and …