Cultivating innovative pragmatic cluster-randomized registry trials embedded in hemodialysis care: workshop proceedings from 2018

EJ Lee, A Patel, RR Acedillo… - … Journal of Kidney …, 2019 - journals.sagepub.com
Hemodialysis is a life-sustaining treatment for persons with kidney failure. However, those
on hemodialysis still face a poor quality of life and a short life expectancy. High-quality …

[HTML][HTML] Risk of rhabdomyolysis with donepezil compared with rivastigmine or galantamine: a population-based cohort study

JL Fleet, E McArthur, A Patel, MA Weir… - CMAJ, 2019 - Can Med Assoc
BACKGROUND: Donepezil, rivastigmine and galantamine are popular cholinesterase
inhibitors used to manage the symptoms of Alzheimer disease and other dementias; regulatory …

Personalised cooler dialysate for patients receiving maintenance haemodialysis (MyTEMP): a pragmatic, cluster-randomised trial

AX Garg, AA Al-Jaishi, SN Dixon, JM Sontrop… - The Lancet, 2022 - thelancet.com
Background Haemodialysis centres have conventionally provided maintenance haemodialysis
using a standard dialysate temperature (eg, 36·5C) for all patients. Many centres now …

A province-wide, cross-sectional study of demographics and medication use of patients in hemodialysis units across Ontario

M Battistella, R Jandoc, JY Ng… - Canadian Journal of …, 2018 - journals.sagepub.com
Background: Hemodialysis patients are at an increased risk of polypharmacy as they have
the highest pill burden of all chronically ill patient populations, with an estimated average of …

Development and validation of nine deprescribing algorithms for patients on hemodialysis to decrease polypharmacy

MJ Lefebvre, PCK Ng, A Desjarlais… - … Journal of Kidney …, 2020 - journals.sagepub.com
Background: Polypharmacy is ubiquitous in patients on hemodialysis (HD), and increases
risk of adverse events, medication interactions, nonadherence, and mortality. Appropriately …

Patient, caregiver, and provider perspectives on challenges and solutions to individualization of care in hemodialysis: a qualitative study

R Sass, J Finlay, K Rossum… - … Journal of Kidney …, 2020 - journals.sagepub.com
Background: Clinical settings often make it challenging for patients with kidney failure to
receive individualized hemodialysis (HD) care. Individualization refers to care that reflects an …

Ethical issues in the design and conduct of pragmatic cluster randomized trials in hemodialysis care: an interview study with key stakeholders

SG Nicholls, K Carroll, C Weijer… - … Journal of Kidney …, 2020 - journals.sagepub.com
Background: Pragmatic cluster randomized trials (CRTs) offer an opportunity to improve health
care by answering important questions about the comparative effectiveness of treatments …

A mixed method investigation to determine priorities for improving information, interaction, and individualization of care among individuals on in-center hemodialysis …

K Rossum, J Finlay, M McCormick… - … Journal of Kidney …, 2020 - journals.sagepub.com
Background: Current health systems do not effectively address all aspects of chronic care.
For better self-management of disease, kidney patients have identified the need for improved …

Voicing individual concerns for engagement in hemodialysis (VOICE-HD): a mixed method, randomized pilot trial of digital health in dialysis care delivery

S Thompson, K Schick-Makaroff… - … Journal of Kidney …, 2021 - journals.sagepub.com
Background: People receiving in-center hemodialysis (HD) have prioritized the need for more
individualized health information and better communication with nephrologists. The most …

Re-envisioning the Canadian Nephrology Trials Network: a Can-SOLVE-CKD stakeholder meeting of patient partners and researchers

A Murdoch, KK Tennankore, C Bohm… - … Journal of Kidney …, 2021 - journals.sagepub.com
Purpose: The Canadian Nephrology Trials Network (CNTN) was formed in 2014 to support
Canadian researchers in developing, designing, and conducting prospective studies in …