We undertook a meta-analysis of six Crohn's disease genome-wide association studies (GWAS)
comprising 6,333 affected individuals (cases) and 15,056 controls and followed up the …

Several risk factors for Crohn's disease have been identified in recent genome-wide association
studies. To advance gene discovery further, we combined data from three studies on …

We present a genome-wide association study of ileal Crohn disease and two independent
replication studies that identify several new regions of association to Crohn disease. …

Genome-wide association studies and candidate gene studies in ulcerative colitis have
identified 18 susceptibility loci. We conducted a meta-analysis of six ulcerative colitis genome-…

Background Although corticosteroids are highly effective in improving symptoms of Crohn's
disease, they may have substantial toxicity. In some patients, attempts to discontinue …

The inflammatory bowel diseases Crohn's disease and ulcerative colitis are common, chronic
disorders that cause abdominal pain, diarrhea, and gastrointestinal bleeding. To identify …

The discovery of a series of genetic and serological markers associated with disease
susceptibility and phenotype in inflammatory bowel disease has led to the prospect of an …

The chronic inflammatory bowel diseases (IBDs)—Crohn disease (CD) and ulcerative colitis
(UC)—are idiopathic, inflammatory disorders of the gastrointestinal tract. These conditions …

Background & Aims Increased intestinal permeability has been associated with Crohn’s
disease (CD), but it is not clear whether it is a cause or result of the disease. We performed a …

Ulcerative colitis is a chronic inflammatory disease of the colon that presents as diarrhea
and gastrointestinal bleeding. We performed a genome-wide association study using DNA …