Fatal poisoning by MDMA (ecstasy) and MDEA: a case report

Int J Legal Med. 1996;108(5):272-5. doi: 10.1007/BF01369826.

Abstract

The first observation of lethal recreational use of MDMA (ecstasy) and MDEA in Italy is reported, together with extensive toxicological and histopathological documentation. Findings such as disseminated intravascular coagulation, rarely reported before, are colocated in the framework of the toxic syndrome for a better definition of criteria for forensic diagnosis.

MeSH terms

  • 3,4-Methylenedioxyamphetamine / analogs & derivatives*
  • 3,4-Methylenedioxyamphetamine / pharmacokinetics
  • 3,4-Methylenedioxyamphetamine / poisoning
  • Capillaries / pathology
  • Designer Drugs / pharmacokinetics
  • Designer Drugs / poisoning*
  • Drug Overdose / blood
  • Drug Overdose / pathology*
  • Fluorescent Antibody Technique
  • Gas Chromatography-Mass Spectrometry
  • Hallucinogens / pharmacokinetics
  • Hallucinogens / poisoning*
  • Humans
  • Kidney Tubules / pathology
  • Lung / blood supply
  • Myoglobinuria / blood
  • Myoglobinuria / chemically induced*
  • Myoglobinuria / pathology
  • N-Methyl-3,4-methylenedioxyamphetamine / pharmacokinetics
  • N-Methyl-3,4-methylenedioxyamphetamine / poisoning*
  • Poisoning / blood
  • Poisoning / pathology*
  • Pulmonary Embolism / blood
  • Pulmonary Embolism / chemically induced
  • Pulmonary Embolism / pathology

Substances

  • Designer Drugs
  • Hallucinogens
  • 3,4-Methylenedioxyamphetamine
  • N-Methyl-3,4-methylenedioxyamphetamine
  • 3,4-methylenedioxyethamphetamine