Bleomycin-induced flagellate dermatitis: a clinical and histopathological review

Br J Dermatol. 1994 Nov;131(5):700-2. doi: 10.1111/j.1365-2133.1994.tb04986.x.

Abstract

We report a case of bleomycin-induced flagellate dermatitis. Our patient developed pruritic linear lesions 4 days after her first dose of bleomycin. A closed patch test was performed, and was negative. However, on rechallenge, the linear eruption recurred in the previously involved sites, and in new sites, within 24 h. Flagellate dermatitis is a characteristic reaction to bleomycin use, but varying histological features and clinical presentations may be seen.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Bleomycin / adverse effects*
  • Drug Eruptions / pathology*
  • Female
  • Humans

Substances

  • Bleomycin