Abstract
Of 21 schizophrenic adolescents given thiothixene or thioridazine, many responded poorly or experienced sedation. Because sedation necessitates dose reductions, which limit therapeutic response, for schizophrenic adolescents high-potency neuroleptics may be preferable to the more sedating low-potency drugs.
Publication types
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Clinical Trial
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Comparative Study
MeSH terms
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Adolescent
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Child
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Clinical Trials as Topic
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Drug Administration Schedule
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Female
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Hospitalization
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Humans
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Male
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Psychiatric Status Rating Scales
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Schizophrenia / drug therapy*
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Schizophrenic Psychology
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Sleep Stages
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Thioridazine / administration & dosage
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Thioridazine / adverse effects
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Thioridazine / therapeutic use*
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Thiothixene / administration & dosage
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Thiothixene / adverse effects
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Thiothixene / therapeutic use*