Abstract
We evaluated the ability of the calcium channel blocker nifedipine to control autonomic hyperreflexia during cystoscopy in 7 patients with cervical spinal cord injuries. Nifedipine (10 mg.) alleviated autonomic hyperreflexia when given sublingually during cystoscopy and prevented autonomic hyperreflexia when given orally 30 minutes before cystoscopy. No adverse drug effects were observed.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Administration, Oral
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Administration, Sublingual
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Adult
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Autonomic Nervous System Diseases / etiology
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Autonomic Nervous System Diseases / prevention & control*
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Cystoscopy / adverse effects*
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Cystoscopy / methods
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Drug Evaluation
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Hemodynamics / drug effects
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Humans
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Male
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Middle Aged
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Nifedipine / administration & dosage*
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Reflex, Abnormal / etiology
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Reflex, Abnormal / prevention & control*
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Spinal Cord Injuries / complications*
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Spinal Cord Injuries / physiopathology