Heyde syndrome: a common diagnosis in older patients with severe aortic stenosis

M W Massyn; S A Khan

doi:10.1093/ageing/afp019

Heyde syndrome: a common diagnosis in older patients with severe aortic stenosis

Age Ageing. 2009 May;38(3):267-70; discussion 251. doi: 10.1093/ageing/afp019. Epub 2009 Mar 10.

Authors

M W Massyn¹, S A Khan

Affiliation

¹ Department of Elderly Care, Lister Hospital, Corey's Mill Lane, Stevenage, Herts SG1 4AB, UK.

PMID: 19276092
DOI: 10.1093/ageing/afp019

Abstract

Heyde syndrome is a triad of aortic stenosis, an acquired coagulopathy and anaemia due to bleeding from intestinal angiodysplasia. The evidence that aortic stenosis is the root cause of this coagulopathy is compelling. Resolution of anaemia usually follows aortic valve replacement. This article discusses studies linking aortic stenosis with other conditions in the triad as well as diagnosis and management of this complex pathology.

Publication types

Review

MeSH terms

Age Factors
Aged
Anemia, Iron-Deficiency / etiology*
Anemia, Iron-Deficiency / pathology
Anemia, Iron-Deficiency / surgery
Angiodysplasia / complications*
Angiodysplasia / pathology
Angiodysplasia / surgery
Aortic Valve Stenosis / complications*
Aortic Valve Stenosis / pathology
Aortic Valve Stenosis / surgery
Gastrointestinal Hemorrhage / etiology*
Gastrointestinal Hemorrhage / pathology
Gastrointestinal Hemorrhage / surgery
Heart Valve Prosthesis Implantation
Humans
Severity of Illness Index
Syndrome
Treatment Outcome
von Willebrand Diseases / etiology*
von Willebrand Diseases / pathology
von Willebrand Diseases / surgery