Documented subacute stent thrombosis within thirty days after stenting with sirolimus-eluting stent (Cypher) for acute myocardial infarction: a Japanese single center retrospective non-randomized study

Circ J. 2006 Aug;70(8):1091-2. doi: 10.1253/circj.70.1091.

Abstract

Background: The incidence of subacute stent thrombosis (SAT) within 30 days after stenting with a sirolimus-eluting stent (Cypher) for acute myocardial infarction (AMI) was retrospectively compared to that with bare-metal stents (BMS).

Methods and results: Among 559 lesions in 558 consecutive AMI from April 2003 to February 2006, the incidence of documented SAT after Cypher implantation (2/276 lesions, 0.72%) was almost the same as for BMS (2 cases, 0.71%). Aspirin (81-100 mg/day) plus ticlopidine (200 mg/day) were administered continuously after admission in all 4 cases.

Conclusion: Documented SAT did not increase after stenting with Cypher for AMI under aspirin plus ticlopidine.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Aspirin / therapeutic use
  • Coronary Restenosis / complications
  • Coronary Thrombosis / epidemiology*
  • Coronary Thrombosis / etiology*
  • Coronary Thrombosis / prevention & control
  • Disease Progression
  • Female
  • Humans
  • Immunosuppressive Agents / administration & dosage
  • Incidence
  • Male
  • Myocardial Infarction / surgery*
  • Platelet Aggregation Inhibitors / therapeutic use
  • Retrospective Studies
  • Sirolimus / administration & dosage
  • Stents / adverse effects*
  • Ticlopidine / therapeutic use
  • Time Factors

Substances

  • Immunosuppressive Agents
  • Platelet Aggregation Inhibitors
  • Ticlopidine
  • Aspirin
  • Sirolimus