An evaluation of radionuclide bone scanning and liver ultrasonography for staging breast cancer

Aust N Z J Surg. 1992 Jul;62(7):550-5. doi: 10.1111/j.1445-2197.1992.tb07049.x.

Abstract

The use of nuclear bone scanning and liver ultrasonography to stage breast cancer is an established practice in many hospitals. A 3 year prospective study was undertaken to assess the usefulness of these two investigations. Three hundred and fifty-eight patients were analysed: 133 had stage I disease, 188 were stage II and 37 were stage III. Bone scans were performed on 339 (94.7%) patients; 302 had stage I or stage II disease; and 37 were stage III. Bone scans were positive for metastases in only 0.9% of stage I and II patients but were positive in 16.2% of patients with stage III disease. None of the 309 (96.2%) stage I or stage II patients who had an ultrasound scan had any liver metastases detected whereas positive scans were obtained in 5.4% of stage III patients. It can be concluded that the incidence of demonstrable bone or liver metastases in stage I and stage II breast cancer patients is so low that the use of routine scanning can be abandoned.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Bone Neoplasms / diagnostic imaging*
  • Bone Neoplasms / epidemiology
  • Bone Neoplasms / secondary
  • Breast Neoplasms / complications
  • Breast Neoplasms / epidemiology
  • Breast Neoplasms / pathology*
  • Female
  • Humans
  • Incidence
  • Liver Neoplasms / diagnostic imaging*
  • Liver Neoplasms / epidemiology
  • Liver Neoplasms / secondary
  • Middle Aged
  • Neoplasm Staging / methods
  • Neoplasm Staging / standards*
  • Northern Ireland / epidemiology
  • Prognosis
  • Prospective Studies
  • Radionuclide Imaging
  • Reproducibility of Results
  • Sensitivity and Specificity