Skip to main content

Advertisement

Log in

Surgery for hip fractures: Does surgical delay affect outcomes?

  • Review Article
  • Published:
Indian Journal of Orthopaedics Aims and scope Submit manuscript

Abstract

Hip fractures are associated with a high rate of mortality and profound temporary and sometimes permanent impairment of quality of life. Current guidelines indicate that surgeons should perform surgery for a hip fracture within 24 hours of injury because earlier surgery is associated with better functional outcome and lower rates of perioperative complications and mortality. Proponents of early treatment argue that this approach minimizes the length of time a patient is confined to bed rest, thereby reducing the risk for associated complications, such as pressure sores, deep vein thrombosis, and urinary tract infections. Those favoring delaying surgery beyond the guideline recommendations believe that this approach is required to medically optimize patients, and therefore decrease the risk for perioperative complications. Further challenges to resolving this debate is the lack of an accepted definition of what should constitute an “unacceptable delay” for hip fracture surgery and the fact that outcomes associated with surgical delay are based on observational data alone (i.e., not randomized controlled trials). The effect of preoperative timing on mortality and other patient-important outcomes across various age groups remains controversial and warrants a large randomized controlled trial to offer clear insights into the effects associated with early versus delayed surgery among hip fracture patients.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Bottle A, Aylin P. Mortality associated with delay in operation after hip fracture: observational study. BMJ 2006;332:947–51.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Weller I, Wai EK, Jaglal S, Kreder HJ. The effect of hospital type and surgical delay on mortality after surgery for hip fracture. J Bone Joint Surg Br 2005;87:361–6.

    Article  CAS  PubMed  Google Scholar 

  3. Johnell O, Kanis JA. An estimate of the worldwide prevalence, mortality and disability associated with hip fracture. Osteoporos Int 2004;15:897–902.

    Article  CAS  PubMed  Google Scholar 

  4. Parker M, Johansen A. Hip fracture. BMJ 2006;333:27–30.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Holt G, Smith R, Duncan K, Hutchison JD, Reid D. Changes in population demographics and the future incidence of hip fracture. Injury 2009;40:722–26.

    Article  CAS  PubMed  Google Scholar 

  6. Ray NF, Chan JK, Thamer M, Melton L J III. Medical expenditures for the treatment of osteoporotic fractures in the United States in 1995: report from the National Osteoporosis Foundation. J Bone Miner Res 1997;12:24–35.

    Article  CAS  PubMed  Google Scholar 

  7. Wiktorowicz ME, Goeree R, Papaioannou A, Adachi JD, Papadimitropoulos E. Economic implications of hip fracture: health service use, institutional care and cost in Canada. Osteoporos Int 2001;12:271–8.

    Article  CAS  PubMed  Google Scholar 

  8. Fractured neck of femur. Prevention and management. Summary and recommendations of a report of the Royal College of Physicians. J R Coll Physicians Lond 1989;23:8–12.

    Google Scholar 

  9. Grimes JP, Gregory PM, Noveck H, Butler MS, Carson JL. The effects of time-to-surgery on mortality and morbidity in patients following hip fracture. Am J Med 2002;112:702–9.

    Article  PubMed  Google Scholar 

  10. Manninger J, Kazar G, Fekete G, Fekete K, Frenyo S, Gyarfas F, et al. Significance of urgent (within 6h) internal fixation in the management of fractures of the neck of the femur. Injury 1989;20:101–5.

    Article  CAS  PubMed  Google Scholar 

  11. Orosz GM, Magaziner J, Hannan EL, Morrison RS, Koval K, Gilbert M, et al. Association of timing of surgery for hip fracture and patient outcomes. JAMA 2004;291:1738–43.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Perez JV, Warwick DJ, Case CP, Bannister GC. Death after proximal femoral fracture - an autopsy study. Injury 1995;26:237–40.

    Article  CAS  PubMed  Google Scholar 

  13. Rogers FB, Shackford SR, Keller MS. Early fixation reduces morbidity and mortality in elderly patients with hip fractures from low-impact falls. J Trauma 1995;39:261–5.

    Article  CAS  PubMed  Google Scholar 

  14. Villar RN, Allen SM, Barnes SJ. Hip fractures in healthy patients: operative delay versus prognosis. Br Med J 1986;293:1203–4.

    Article  CAS  Google Scholar 

  15. Information Services Division. Clinical decision-making: is the patient fit for theatre? A report from the Scottish Hip Fracture Audit. http://www.shfa.scot.nhs.uk/Theatre_Delay_Report.pdf. Edinburgh: ISD Scotland Publications; 2008.

    Google Scholar 

  16. Lyons AR. Clinical outcomes and treatment of hip fractures. Am J Med 1997;103:51–63.

    Article  Google Scholar 

  17. Dorotka R, Schoechtner H, Buchinger W. The influence of immediate surgical treatment of proximal femoral fractures on mortality and quality of life: operation within six hours of the fracture versus later than six hours. J Bone Joint Surg Br 2003;85:1107–13.

    Article  CAS  PubMed  Google Scholar 

  18. Hulley S, Cummings S, Browner W, Grady D, Newman T. Designing Clinical Research. 3rd ed. Philadelphia: Lippincott Williams and Wilkins; 2007.

    Google Scholar 

  19. Shiga T, Wajima Z, Ohe Y. Is operative delay associated with increased mortality of hip fracture patients? Systematic review, meta-analysis, and meta-regression. Can J Anaesth 2008;55:146–54.

    Article  PubMed  Google Scholar 

  20. Hamlet WP, Lieberman JR, Freedman EL, Dorey FJ, Fletcher A, Johnson EE. Influence of health status and the timing of surgery on mortality in hip fracture patients. Am J Orthop 1997;26:621–7.

    CAS  PubMed  Google Scholar 

  21. Hardin GT. Timing of fracture fixation: a review. Orthop Rev 1990;19:861–7.

    CAS  PubMed  Google Scholar 

  22. Majumdar SR, Beaupre LA, Johnston DW, Dick DA, Cinats JG, Jiang HX. Lack of association between mortality and timing of surgical fixation in elderly patients with hip fracture: results of a retrospective population-based cohort study. Med Care 2006;44:552–9.

    Article  CAS  PubMed  Google Scholar 

  23. Rae HC, Harris IA, McEvoy L, Todorova T. Delay to surgery and mortality after hip fracture. Aust N Z J Surg 2007;77:889–91.

    Article  Google Scholar 

  24. Beringer TR, Crawford VL, Brown JG. Audit of surgical delay in relationship to outcome after proximal femoral fracture. Ulster Med J 1996;65:32–8.

    CAS  PubMed  PubMed Central  Google Scholar 

  25. Smektala R, Dasch B, Endres H, Lungenhausen M, Mayer C, Bonnaire F, et al. The effect of time-to-surgery on outcome in elderly patients with proximal femoral fractures. Polski Przeglad Chirurgiczny 2007;79:177–88.

    Article  Google Scholar 

  26. Zuckerman JD, Skovron ML, Koval KJ, Aharonoff G, Frankel VH. Postoperative complications and mortality associated with operative delay in older patients who have a fracture of the hip. J Bone Joint Surg Am 1995;77:1551–6.

    Article  CAS  PubMed  Google Scholar 

  27. Al-Ani AN, Samuelsson B, Tidermark J, Norling A, Ekstrom W, Cederholm T, et al. Early operation on patients with a hip fracture improved the ability to return to independent living: a prospective study of 850 patients. J Bone Joint Surg Am 2008;90:1436–42.

    Article  PubMed  Google Scholar 

  28. Casaletto JA, Gatt R. Post-operative mortality related to waiting time for hip fracture surgery. Injury 2004;35:114–20.

    Article  PubMed  Google Scholar 

  29. Charalambous CP, Yarwood S, Paschalides C, Siddique I, Paul A, Hirst P. Reduced delays in A&E for elderly patients with hip fractures. Ann R Coll Surg Eng 2003;85:200–3.

    Article  CAS  Google Scholar 

  30. Elliott J, Beringer T, Kee F, Marsh D, Willis C, Stevenson M. Predicting survival after treatment for fracture of the proximal femur and the effect of delays to surgery. JCE 2003;56:788–95.

    CAS  PubMed  Google Scholar 

  31. Holt G, Smith R, Duncan K, Finlayson DF, Gregori A. Early mortality after surgical fixation of hip fractures in the elderly: an analysis of data from the Scottish Hip Fracture Audit. J Bone Joint Surg Br 2008;90:1357–63.

    Article  CAS  PubMed  Google Scholar 

  32. Moran CG, Wenn RT, Sikand M, Taylor AM. Early mortality after hip fracture: is delay before surgery important? J Bone Joint Surg Am 2005;87:483–9.

    PubMed  Google Scholar 

  33. Orosz GM, Hannan EL, Magaziner J, Koval K, Gilbert M, Aufses A, et al. Hip fracture in the older patient: reasons for delay in hospitalization and timing of surgical repair. J Am Geriatr Soc 2002;50:1336–40.

    Article  PubMed  Google Scholar 

  34. Parker MJ, Pryor GA. The timing of surgery for proximal femoral fractures. J Bone Joint Surg Br 1992;74:203–5.

    Article  CAS  PubMed  Google Scholar 

  35. Siegmeth AW, Gurusamy K, Parker MJ. Delay to surgery prolongs hospital stay in patients with fractures of the proximal femur. J Bone Joint Surg Br 2005;87:1123–6.

    Article  CAS  PubMed  Google Scholar 

  36. Smektala R, Wenning M, Luka M. Early surgery after hip para-articular femoral fracture: results of a prospective study of surgical timing in 161 elderly patients. Zentralblatt fur Chirurgie 2000;125:744–9.

    Article  CAS  PubMed  Google Scholar 

  37. Stoddart J, Horne G, Devane P. Influence of preoperative medical status and delay to surgery on death following a hip fracture. Aust N Z J Surg 2002;72:405–7.

    Article  Google Scholar 

  38. Von Meibom N, Gilson N, Dhapre A, Davis B. Operative delay for fracture of the hip: a two-centre prospective study. J Bone Joint Surg Br 2007;89:77–9.

    Article  Google Scholar 

  39. Kenzora JE, McCarthy RE, Lowell JD, Sledge CB. Hip fracture mortality: relation to age, treatment, preoperative illness, time of surgery, and complications. Clin Orthop 1984;186:45–56.

    Google Scholar 

  40. Zagrodnick J, Kaufner HK. Decreasing risk by individualized timing of surgery of para-articular femoral fractures of the hip in the elderly. Unfallchirurgie 1990;16:139–43.

    Article  CAS  PubMed  Google Scholar 

  41. Mullen J, Mullen N. Hip fracture mortality: a prospective, multifactorial study to predict and minimize death risk. Clin Orthop 1992;280:214–22.

    Google Scholar 

  42. Hoerer D, Volpin G, Stein H. Results of early and delayed surgical fixation of hip fractures in the elderly: a comparative retrospective study. Bull Hosp Jt Dis 1993;53:29–33.

    CAS  PubMed  Google Scholar 

  43. Sexson SB, Lehner JT. Factors affecting hip fracture mortality. J Orthop Trauma 1987;1:298–305.

    Article  CAS  PubMed  Google Scholar 

  44. Bredahl C, Nyholm B, Hindsholm KB, Mortensen JS, Olesen AS. Mortality after hip fracture: results of operation within 12 h of admission. Injury 1992;23:83–6.

    Article  CAS  PubMed  Google Scholar 

  45. Hommel A, Ulander K, Bjorkelund KB, Norrman PO, Wingstrand H, Thorngren KG. Influence of optimised treatment of people with hip fracture on time to operation, length of hospital stay, reoperations and mortality within 1 year. Injury 2008;39:1164–74.

    Article  PubMed  Google Scholar 

  46. Verbeek DO, Ponsen KJ, Goslings JC, Heetveld MJ. Effect of surgical delay on outcome in hip fracture patients: a retrospective multivariate analysis of 192 patients. Int Orthop 2008;32:13–8.

    Article  CAS  PubMed  Google Scholar 

  47. Gdalevich M, Cohen D, Yosef D, Tauber C. Morbidity and mortality after hip fracture: the impact of operative delay. Arch Orthop Trauma Surg 2004;124:334–40.

    Article  PubMed  Google Scholar 

  48. McGuire KJ, Bernstein J, Polsky D, Silber JH. The 2004 Marshall Urist award: delays until surgery after hip fracture increases mortality. Clin Orthop 2004;428:294–301.

    Article  Google Scholar 

  49. Novack V, Jotkowitz A, Etzion O, Porath A. Does delay in surgery after hip fracture lead to worse outcomes? A multicenter survey. Int J Qual Health Care 2007;19:170–6.

    Article  PubMed  Google Scholar 

  50. Bergeron E, Lavoie A, Moore L, Bamvita JM, Ratte S, Gravel C, et al. Is the delay to surgery for isolated hip fracture predictive of outcome in efficient systems? J Trauma 2006;60:753–7.

    Article  PubMed  Google Scholar 

  51. Sebestyen A, Boncz I, Sandor J, Nyarady J. Effect of surgical delay on early mortality in patients with femoral neck fracture. Int Orthop 2008;32:375–9.

    Article  PubMed  Google Scholar 

  52. Williams A, Jester R. Delayed surgical fixation of fractured hips in older people: impact on mortality. J Adv Nurs 2005;52:63–9.

    Article  PubMed  Google Scholar 

  53. Hoenig H, Rubenstein LV, Sloane R, Horner R, Kahn K. What is the role of timing in the surgical and rehabilitative care of Simunovic, et al.: Timing of surgery for hip fracture community-dwelling older persons with acute hip fracture? Arch Intern Med 1997;157:513–20.

    Article  CAS  PubMed  Google Scholar 

  54. Haleem S, Heinert G, Parker MJ. Pressure sores and hip fractures. Injury 2008;39:219–23.

    Article  CAS  PubMed  Google Scholar 

  55. Jain R, Koo M, Kreder HJ, Schemitsch EH, Davey JR, Mahomed NN. Comparison of early and delayed fixation of subcapital hip fractures in patients sixty years of age or less. J Bone Joint Surg Am 2002;84:1605–12.

    Article  PubMed  Google Scholar 

  56. Cree AK, Nade S. How to predict return to the community after fractured proximal femur in the elderly. Aust N Z J Surg 1999;69:723–5.

    Article  CAS  PubMed  Google Scholar 

  57. Bhandari M, Devereaux PJ, Swiontkowski MF, Tornetta P, Obremskey W, Koval KJ, et al. Internal fixation compared with arthroplasty for displaced fractures of the femoral neck: a metaanalysis. J Bone Joint Surg Am 2003;85:1673–81.

    Article  PubMed  Google Scholar 

  58. Whinney CM. Do hip fractures need to be repaired within 24 hours of injury? Cleve Clin J Med 2005;72:250–2.

    Article  PubMed  Google Scholar 

  59. Doruk H, Mas MR, Yildiz C, Sonmez A, Kyrdemir V. The effect of the timing of hip fracture surgery on the activity of daily living and mortality in elderly. Arch Gerontol Geriatr 2004;39:179–85.

    Article  PubMed  Google Scholar 

  60. Lefaivre KA, Macadam SA, Davidson DJ, Gandhi R, Chan H, Broekhuyse HM. Length of stay, mortality, morbidity and delay to surgery in hip fractures. J Bone Joint Surg Br 2009;91:922–7.

    Article  CAS  PubMed  Google Scholar 

  61. Thomas S, Ord J, Pailthorpe C. A study of waiting time for surgery in elderly patients with hip fracture and subsequent in-patient hospital stay. Ann R Coll Surg Eng 2001;83:37–9.

    CAS  Google Scholar 

  62. Papadimitropoulos EA, Coyte PC, Josse RG, Greenwood CE. Current and projected rates of hip fracture in Canada. CMAJ 1997;157:1357–63.

    CAS  PubMed  PubMed Central  Google Scholar 

  63. Braithwaite RS, Col NF, Wong JB. Estimating hip fracture morbidity, mortality and costs. J Am Geriatr Soc 2003;51:364–70.

    Article  PubMed  Google Scholar 

  64. Shabat S, Heller E, Mann G, Gepstein R, Fredman B, Nyska M. Economic consequences of operative delay for hip fractures in a non-profit institution. Orthopedics 2003;26:1197–9.

    PubMed  Google Scholar 

  65. Nigwekar SU, Rajda J, Navaneethan SD. Hospitalist care and length of stay in patients with hip fracture: a systematic review. Arch Int Med 2008;168:1010–1.

    Article  Google Scholar 

  66. Bhattacharyya T, Vrahas MS, Morrison SM, Kim E, Wiklund RA, Smith RM, et al. The value of the dedicated orthopaedic trauma operating room. J Trauma 2006;60:1336–40.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Nicole Simunovic.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Simunovic, N., Devereaux, P.J. & Bhandari, M. Surgery for hip fractures: Does surgical delay affect outcomes?. IJOO 45, 27–32 (2011). https://doi.org/10.4103/0019-5413.73660

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.4103/0019-5413.73660

Key words

Navigation