Clinical ResearchHeart FailureRelationship of Serum Digoxin Concentration to Mortality and Morbidity in Women in the Digitalis Investigation Group Trial: A Retrospective Analysis
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Drs. Adams, Patterson, O’Connor, Gattis, and Gheorghiade have or have had consulting, research relationships, and speaker bureau support from GlaxoSmithKline related to carvedilol but not digoxin. The DIG is conducted and supported by the National Heart, Lung, and Blood Institute (NHLBI) in collaboration with the DIG Study Investigators. This manuscript was not prepared in collaboration with investigators of the DIG Study and does not necessarily reflect the opinions or views of the DIG Study or the NHLBI. The authors would like to dedicate this manuscript to the late Dr. Thomas W. Smith, whose sense of scholarship, high ideals, good nature, and untiring investigative efforts related to the use of digitalis in patients with heart failure inspired this work.