Progress in cardiologyInterstudy reproducibility of right ventricular volumes, function, and mass with cardiovascular magnetic resonance☆
Section snippets
Study population
The population has been previously reported on for assessment of reproducibility of LV functional parameters.4 In brief, we investigated 60 subjects (47 men; mean age, 51 ± 18 years). The study group consisted of 20 healthy volunteers without cardiac history or risk factors, 20 patients with previously documented LV hypertrophy (LVH), and 20 patients with stable congestive heart failure (CHF) of ischemic or dilated cardiomyopathy origin who had a dilated left ventricle with systolic dysfunction
Results
CMR was well tolerated by all subjects. The age and sex distribution of all 3 subgroups and the RV parameters are listed in Table I. Healthy subjects were significantly younger than members of the other 2 groups (P <.001), but there were no differences in body habitus. RV EDV, ESV, and mass were comparable in the subgroups. RV stroke volume and EF were decreased in the heart failure group compared with healthy subjects and paients with LVH (P <.01).
Importance of the right ventricle
The importance of the right ventricle in cardiac disease has been underestimated in the past, and early reports suggested that RV pump function is not relevant to overall cardiac function.25, 26 More recent studies show, however, that RV function is a major determinant of prognosis in myocardial infarction27 and cardiac symptoms and exercise capacity in chronic heart failure.28, 29 Similarly, RV function in congenital heart disease is a key clinical issue.30 Because of ventricular interaction,
References (50)
- et al.
Dimensional accuracy of magnetic resonance in studies of the heart
Lancet
(1985) - et al.
Comparison of interstudy reproducibility of cardiovascular magnetic resonance with two-dimensional echocardiography in normal subjects and in patients with heart failure or left ventricular hypertrophy
Am J Cardiol
(2002) - et al.
Interstudy reproducibility of dimensional and functional measurements between cine magnetic resonance imaging studies in the morphologically abnormal left ventricle
Am Heart J
(1990) - et al.
Rapid, accurate and simultaneous assessment of right and left ventricular mass with nuclear magnetic resonance imaging using the snapshot gradient method
J Am Coll Cardiol
(1992) - et al.
Assessment of right ventricular diastolic and systolic function in patients with dilated cardiomyopathy using cine magnetic resonance imaging
Am Heart J
(1991) - et al.
Direct quantitation of right and left ventricular volumes with nuclear magnetic resonance imaging in patients with primary pulmonary hypertension
J Am Coll Cardiol
(1992) - et al.
Estimation of right ventricular mass in normal subjects and in patients with primary pulmonary hypertension by nuclear magnetic resonance imaging
J Am Coll Cardiol
(1993) - et al.
Measurement of right ventricular mass in normal and dilated cardiomyopathic ventricles using cine magnetic resonance imaging
Am J Cardiol
(1992) - et al.
The absence of conspicuous increments in venous pressure after severe damage to the right ventricle of the dog and discussion of the relation between clinical congestive heart failure and heart disease
Am Heart J
(1943) - et al.
Clinical assessment and follow up of functional capacity in patients with chronic congestive cardiomyopathy
Am J Cardiol
(1982)
Relation of right ventricular ejection fraction to exercise capacity of patients with chronic left ventricular failure
Am J Cardiol
Excessive right ventricular hypertrophic response in adults with the mustard procedure for transposition of the great arteries
Am J Cardiol
Contractile mechanics and interaction of the right and left ventricles
Am J Cardiol
Reduced right ventricular ejection fraction as a marker for idiopathic dilated cardiomyopathy compared with ischemic left ventricular dysfunction
Am Heart J
Right ventricular functionmethodologic and clinical considerations in noninvasive scintigraphic assessment
J Am Coll Cardiol
Rapid, accurate and simultaneous noninvasive assessment of right and left ventricular mass with nuclear magnetic resonance imaging using the snapshot gradient method
J Am Coll Cardiol
Reproducibility of MRI-derived measurements of right ventricular volumes and myocardial mass
Magn Reson Imaging
Measurement of right and left ventricular volumes in healthy individuals with cine MR imaging
Radiology
In vivo validation of magnetic resonance velocity imaging
J Comput Assist Tomogr
Normal left ventricular dimensions and functioninterstudy reproducibility of measurements with cine MR imaging
Radiology
Left ventricular measurements with cine and spin-echo MR imaginga study of reproducibility with variance component analysis
Radiology
Reduction in sample size for studies of remodelling in heart failure by the use of cardiovascular magnetic resonance
J Cardiovasc Magn Reson
Normal human right and left ventricular mass, systolic function and gender differences by cine magnetic resonance imaging
J Cardiovasc Magn Reson
Measurement of ventricular volumes in the dog by nuclear magnetic resonance imaging
J Am Coll Cardiol
Evaluation of right ventricular volumes measured by magnetic resonance imaging
Eur Heart J
Cited by (0)
- ☆
Supported by CORDA and the Wellcome Trust (London, UK), ADUMED Foundation (Zurich, Switzerland), GlaxoSmithKline (Harlow, UK), and the British Heart Foundation (London, UK).