Elsevier

The Lancet

Volume 347, Issue 9009, 27 April 1996, Page 1181
The Lancet

Letters to the Editor
New variant of Creutzfeldt-Jakob disease in a 26-year-old French man

https://doi.org/10.1016/S0140-6736(96)90638-8Get rights and content

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    Variant CJD was first reported in 1996 in a short series of unusually young British patients with neuropathologically confirmed CJD (Will et al., 1996). A case was recognized in France soon after (Chazot et al., 1996) and, until now, a total of 229 probable and definite vCJD cases has been diagnosed worldwide, France being the most affected country after the UK. The phenotype of vCJD is not so far from kuru and is characterized by the frequent occurrence of psychiatric symptoms (depression, anxiety, apathy, withdrawal and delusions) and atypical pain in limbs or face at clinical onset.

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