Comparison of different methods for assessing sympathovagal balance in chronic congestive heart failure secondary to coronary artery disease☆
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Device-Based Modulation of the Autonomic Nervous System
2016, Clinical Cardiac Pacing, Defibrillation and Resynchronization TherapyNovel Interventional Therapies to Modulate the Autonomic Tone in Heart Failure
2015, JACC: Heart FailureCitation Excerpt :Semiquantitative measures of MIBG imaging such as reduced heart-to-mediastinal (H/M) ratio or reduced washout rate of radiotracer have been predictive of arrhythmia and adverse cardiovascular events, even after accounting for standard predictors as demonstrated in the ADMIRE-HF (AdreView Myocardial Imaging for Risk Evaluation in Heart Failure) trial (54). Most practical in the noninvasive assessment of ANS activity are electrocardiographic surrogates including resting HR, frequency and time domain analysis of HR variability (HRV), provocative maneuvers assessing baroreflex sensitivity, and measures of heart recovery following exercise (55–59). Resting HR has been viewed simplistically as a measure of the net effect of SNS and PNS input to the sinus node, although this obviously has its limitations as a static assessment (59).
Section 6: Nonpharmacologic Management and Health Care Maintenance in Patients With Chronic Heart Failure
2010, Journal of Cardiac FailureCitation Excerpt :Exercise training was found to have physiological benefits in patients with HF. Exercise training improved autonomic dysfunction and heart rate variability and was associated with a fall in resting plasma norepinephrine levels.67,79–82 It was found to improve exercise cardiac output, decrease peripheral vascular tolerance, and produce favorable changes in skeletal muscle metabolism and structure.83,84
Modified orthostatic load for spectral analysis of short-term heart rate variability improves the sensitivity of autonomic dysfunction assessment
2010, Journal of Diabetes and its ComplicationsCitation Excerpt :Analysis of heart rate variability (HRV) allows indirect assessment of cardiac autonomic control. Evaluation of HRV permits the diagnosis of autonomic dysfunction in diabetes (American Diabetes Association: Diabetic Neuropathy, 1996; Maser & Lenhard, 2005; Vinik & Mehrabyan, 2004; Ziegler et al., 1992) and risk stratification in congestive heart failure and/or coronary heart disease (Adamopoulos et al., 1992; American College of Cardiology Cardiovascular Technology Assessment Committee, 1993; Nolan et al., 1998; Task Force of the European Society of Cardiology & North American Society of Pacing and Electrophysiology, 1996). Clinical evidence was found for the association between incidence of lethal arrhythmias and signs of an increased sympathetic and reduced vagal activity (Kleiger, Miller, Bigger, & Moss, Multicentre Post Infarction Research Group, 1987; Malliani, Lombardi, Pagani, & Cerutti, 1994; Priori et al., 2001).
Assessment of Autonomic Function in Cardiovascular Disease. Physiological Basis and Prognostic Implications
2008, Journal of the American College of CardiologyCitation Excerpt :In one study of healthy subjects, a moderate correlation between mean HR and time domain measures of HRV on 24-h ambulatory electrocardiograms was demonstrated (54). However, several other investigations in patients with coronary artery disease or heart failure found no significant correlation between mean, minimum, or maximum HR and time or frequency domain measures of HRV (55–57). The prognostic significance of HRV in cardiovascular disease is widely reported.
Depression, heart rate variability, and exercise training in dialysis patients
2010, European Journal of Cardiovascular Prevention and Rehabilitation
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This study was supported by the British Heart Foundation, London; Eli Lilly, Basingstoke, Hampshire; ICI, Macclesfield; and Squibb, London, United Kingdom.