Skip to main content
SpringerLink
Log in
Book cover

Progress in Iron Research pp 219–228Cite as

Iron Deficiency: The Global Perspective

  • Chapter

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 356))

Abstract

Micronutrient deficiency is increasingly recognized as a priority nutritional problem in the developing world; at least 20% of the world’s population is at risk of a deficiency in vitamin A, iodine, or iron (Trowbridge et al. 1993). Vitamin A deficiency is the most important cause of preventable blindness whereas iodine deficiency is a significant cause of permanent brain damage, mental retardation, and reproductive failure. A deficiency of either of these nutrients is associated with a decrease in childhood survival.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Ballot, D.E., MacPhail, A.P., Bothwell, T.H., Gillooly, M. and Mayet, F.G. 1989, Fortification of curry powder with NaFe(111)EDTA in an iron-deficient population: report of a controlled iron-fortification trial. Am J Clin Nutr 49: 162.

    PubMed  CAS  Google Scholar 

  • Basta, S.S., Soekirman, M.S., Karyadi, D. and Scrimshaw, N.S. 1979, Iron deficiency anemia and the productivity of adult males in Indonesia. Am J Clin Nutr 32: 916.

    PubMed  CAS  Google Scholar 

  • Beguin, Y. 1992, The soluble transferrin receptor: Biological aspects and clinical usefulness as quantitative measure of erythropoiesis. Haematologica 77: 1.

    PubMed  CAS  Google Scholar 

  • Carriaga, M.T., Skikne, B.S., Finley, B., Cutler, B. and Cook, J.D. 1991, Serum transferrin receptor for the detection of iron deficiency in pregnancy. Am J Clin Nutr 54: 1077.

    PubMed  CAS  Google Scholar 

  • Cook, J.D., Alvarado, J., Gutniskey, A., Jamra, M., Labardini, J., Layrisse, M., Linares, J., Loria, A., Maspes, V., Restrepo, A., Reynafarje, C, Sanchez-Medal, L., Velez, H. and Viteri, F. 1971, Nutritional deficiency and anemia in Latin America: a collaborative study. Blood 38: 591.

    PubMed  CAS  Google Scholar 

  • Cook, J.D., Carriaga, M., Kahn, S.G., Schalch, W. and Skikne, B.S. 1990, Gastric delivery system for iron supplementation. Lancet 335: 1136.

    Article  PubMed  CAS  Google Scholar 

  • Cook, J.D., Skikne, B.S. and Baynes, R.D. 1993, Serum transferrin receptor. Annu Rev Med 44: 63.

    Article  PubMed  CAS  Google Scholar 

  • DeMaeyer, E. and Adiels-Tegman, M. 1985, The prevalence of anaemia in the world. Wld Hlth Statist Quart 38: 302.

    CAS  Google Scholar 

  • Ferguson, B J., Skikne, B.S., Simpson, K.M., Baynes, R.D. and Cook, J.D. 1992, Serum transferrin receptor distinguishes the anemia of chronic disease from iron deficiency anemia. J Lab Clin Med 119: 385.

    PubMed  CAS  Google Scholar 

  • Flowers, C.H., Skikne, B.S., Covell, A.M. and Cook, J.D. 1989, The clinical measurement of serum transferrin receptor. J Lab Clin Med 114: 368.

    PubMed  CAS  Google Scholar 

  • Garby, L. and Areekul, S. 1974, Iron supplementation in Thai fish-sauce. Ann Trop Med Parasitol 68: 467.

    PubMed  CAS  Google Scholar 

  • Gam, S.M., Ridella, S.A., Tetzold, A.S. and Falkner, F. 1981, Maternal haematological levels and pregnancy outcomes. Semin Perinatol 5: 155.

    Google Scholar 

  • Gillespie, S., Kevany, J. and Mason, J. 1991, Controlling Iron Deficiency-A Report based on a ACC/SCN Workshop, Lavenham Press Ltd., Suffolk, England.

    Google Scholar 

  • Hallberg, L. 1992, Iron balance in pregnancy and lactation, in: Nutritional Anemias, Nestle Nutrition Workshop Series, Vol. 30, S.J. Fomon and S. Zlotkin. eds., Nestec Ltd., Vevey/Raven Press, New York.

    Google Scholar 

  • Huebers, H.A., Beguin, Y., Pootrakul, P., Einspahr, D. and Finch, C.A. 1990, Intact transferrin receptors in human plasma and their relation to erythropoiesis. Blood 75: 102.

    PubMed  CAS  Google Scholar 

  • Huebers, H.A. and Finch, C.A. 1987, The physiology of transferrin and transferrin receptors. Physiol Rev 67: 520.

    PubMed  CAS  Google Scholar 

  • Idjradinata, P. and Pollitt, E. 1993, Reversal of developmental delays in iron-deficient anaemic infants treated with iron. Lancet 341: 1.

    Article  PubMed  CAS  Google Scholar 

  • Kohgo, Y. 1986, Structure of transferrin and transferrin receptor. Acta Haematol Jpn 49: 1627.

    CAS  Google Scholar 

  • Kohgo, Y., Nishisato, T., Kondo, H., Tsushima, N., Niitsu, Y. and Urushizaki, I. 1986, Circulating transferrin receptor in human serum. Br J Haematol 64: 277.

    Article  PubMed  CAS  Google Scholar 

  • Levin, H.M. 1986, A benefit-cost analysis of nutritional programs for anaemia reduction. Res Observ 1: 219.

    Article  Google Scholar 

  • Lieberman, E., Ryan, K.J., Monson, R.R. and Schoenbaum, S.C. 1988, Association of maternal hematocrit with premature labor. Am J Obstet Gynecol 159: 107.

    PubMed  CAS  Google Scholar 

  • Lozoff, B., Brittenham, G.M., Viteri, F.E., Wolf, A.W. and Urrutia, JJ. 1982, The effects of short-term oral iron therapy on developmental deficits in iron-deficient anemic infants. J Pediatr 100: 351.

    Article  PubMed  CAS  Google Scholar 

  • Lozoff, B., Brittenham, G.M., Wolf, A.W., McClish, D.K., Kuhnert, P.M., Jimenez, E., Jimenez, R., Mora, L.A., Gomez, I. and Krauskoph, D. 1987, Iron deficiency anemia and iron therapy: Effects on infant developmental test performance. Pediatrics 79: 981.

    PubMed  CAS  Google Scholar 

  • Lozoff, B., Jimenez, E. and Wolf, A.W. 1991, Long-term developmental outcome of infants with iron deficiency. N Engl J Med 325: 687.

    Article  PubMed  CAS  Google Scholar 

  • Murphy, J.F., O’Riordan, J., Newcombe, R.G., Coles, E.C. and Pearson, J.F. 1986, Relation of haemoglobin levels in first and second trimesters to outcome of pregnancy. Lancet 1: 992.

    Article  PubMed  CAS  Google Scholar 

  • Ohira, Y., Edgerton, V.R., Gardner, G.W., Senewiratne, B., Barnard, R.J. and Simpson, D.R. 1979, Work capacity, heart rate and blood lactate responses to iron treatment. Br J Haematol 41: 365.

    Article  PubMed  CAS  Google Scholar 

  • Oski, F.A., Honig, A.S., Helu, B. and Howanitz, P. 1983, Effect of iron therapy on behavior performance in nonanemic, iron-deficient infants. Pediatrics 71: 877.

    PubMed  CAS  Google Scholar 

  • Oski, F.A. and Honig, A.S. 1978, The effects of therapy on the developmental scores of iron-deficient infants. J Pediatr 92: 21.

    Article  PubMed  CAS  Google Scholar 

  • Salonen, J.T., Nyyssonen, K., Korpela, H., Tuomilehto, J., Seppanen, R. and Salonen, R. 1992, High stored iron levels are associated with excess risk of myocardial infarction in Eastern Finnish men. Circulation 86: 803.

    Article  PubMed  CAS  Google Scholar 

  • Scholl, T.O., Hediger, M.L., Fischer, R.L. and Shearer, J.W. 1992, Anemia vs iron deficiency: increased risk of preterm delivery in a prospective study. Am J Clin Nutr 55: 985.

    PubMed  CAS  Google Scholar 

  • Schultink, W., van der Ree, M., Matulessi, P. and Gross, R. 1993, Low compliance with an iron-supplementation program: A study among pregnant women in Jakarta, Indonesia. Am J Clin Nutr 57: 135.

    PubMed  CAS  Google Scholar 

  • Shih, Y.J., Baynes, R.D., Hudson, B.G., Flowers, C.H., Skikne, B.S. and Cook, J.D. 1990, Serum transferrin is a truncated form of tissue receptor. J Biol Chem 265: 19077.

    PubMed  CAS  Google Scholar 

  • Simmons, W.K., Cook, J.D., Bingham, K.C., Thomas, M., Jackson, J., Jackson, M., Ahluwalia, N., Kahn, S.G. and Patterson, A.W. 1993, Evaluation of a gastric delivery system for iron supplementation in pregnancy. Am J Clin Nutr (In Press)

    Google Scholar 

  • Skikne, B.S., Flowers, C.H. and Cook, J.D. 1990, Serum transferrin receptor: A quantitative measure of tissue iron deficiency. Blood 75: 1870.

    PubMed  CAS  Google Scholar 

  • Stevens, R.G., Jones, D.Y., Micozzi, M.S. and Taylor, P.R. 1988, Body iron stores and the risk of cancer. N Engl J Med 319: 1047.

    Article  PubMed  CAS  Google Scholar 

  • Trowbridge, F.L., Harris, S.S., Cook, J., Dunn, J.T., Florentino, R.F., Kodyat, B.A., Mannar, M.G.V., Reddy, V., Tontisirin, K., Underwood, B.A. and Yip, R. 1993, Coordinated strategies for controlling micronutrient malnutrition: A technical workshop. J Nutr 123: 775.

    PubMed  CAS  Google Scholar 

  • Viteri, F.E., Alvarez, E., Pinedor, O. and Torun, B. 1983, Prevention of iron deficiency by means of iron fortification of sugar, in: Nutrition intervention Strategies in National Development, B.A. Underwood, ed., Academic Press, New York. 287

    Google Scholar 

  • Walter, T., Kovalskys, J. and Stekel, A. 1983, Effect of mild iron deficiency on infant mental development scores. J Pediatr 102: 519.

    Article  PubMed  CAS  Google Scholar 

  • Walter, T., De Andraca, I., Chadud, P. and Perales, C.G. 1989, Iron deficiency anemia: Adverse effects on infant psychomotor development. Pediatrics 84: 7.

    PubMed  CAS  Google Scholar 

  • Walter, T. 1992, Early and long-term effect of iron deficiency anemia on child development. in: Nutritional Anemias, Nestle Nutrition Workshop Series, Vol. 30, S.J. Fomon and S. Zlotkin eds., Nestec Ltd., Vevey/Raven Press, Ltd., New York. 81

    Google Scholar 

  • Ward, J.H. 1987, The structure, function, and regulation of transferrin receptors. Invest Radiol 22 : 74.

    Article  PubMed  CAS  Google Scholar 

  • Working Group on Fortification of Salt with Iron. 1982, Use of common salt fortified with iron in the control and prevention of anemia-a collaborative study. Am J Clin Nutr 35: 1442.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Hematology Department of Medicine, University of Kansas Medical Center, Kansas City, KS, 66160-7402, USA

    James D. Cook, Barry S. Skikne & Roy D. Baynes

Authors
  1. James D. Cook
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Barry S. Skikne
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Roy D. Baynes
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Shaare Zedek Medical Center and Hebrew University of Jerusalem, Jerusalem, Israel

    Chaim Hershko

  2. The Hebrew University Hadassah Medical School, Jerusalem, Israel

    Abraham M. Konijn

  3. Albert Einstein College of Medicine, Bronx, New York, USA

    Philip Aisen

Rights and permissions

Reprints and permissions

Copyright information

© 1994 Springer Science+Business Media New York

About this chapter

Cite this chapter

Cook, J.D., Skikne, B.S., Baynes, R.D. (1994). Iron Deficiency: The Global Perspective. In: Hershko, C., Konijn, A.M., Aisen, P. (eds) Progress in Iron Research. Advances in Experimental Medicine and Biology, vol 356. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2554-7_24

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-2554-7_24

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6090-2

  • Online ISBN: 978-1-4615-2554-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation