Baseline characteristics of patients with a diagnosis of diabetes, peripheral artery disease or both who underwent lower-extremity amputations
| Characteristic | No. (%) of patients* | |
|---|---|---|
| Any amputation n = 20 062 | Major amputation n = 12 786 | |
| Age, yr, mean ± SD | 68.7 ± 12.4 | 69.8 ± 12.3 |
| Sex, female | 6497 (32.4) | 4349 (34.0) |
| Rural residence† | n = 20 040 3775 (18.8) | n = 12 769 2215 (17.3) |
| Neighbourhood income quintile† | n = 19 818 | n = 12 619 |
| 1 (lowest) | 5529 (27.9) | 3621 (28.7) |
| 2 | 4264 (21.5) | 2660 (21.1) |
| 3 | 3761 (19.0) | 2419 (19.2) |
| 4 | 3414 (17.2) | 2148 (17.0) |
| 5 (highest) | 2850 (14.4) | 1771 (14.0) |
| Immigrant | 878 (4.4) | 573 (4.5) |
| Long-term care residence | 1737 (8.7) | 1572 (12.3) |
| Charlson Comorbidity Index score | ||
| 0 | 1357 (6.8) | 478 (3.7) |
| 1 | 3096 (15.4) | 2079 (16.3) |
| ≥ 2 | 15 609 (77.8) | 10 229 (80.0) |
| PAD and diabetes | ||
| PAD | 18 822 (93.8) | 12 374 (96.8) |
| Diabetes | 16 408 (81.8) | 9967 (78.0) |
| PAD and diabetes | 15 168 (75.6) | 9555 (74.7) |
| Previous peripheral revascularization | 3502 (17.5) | 2962 (23.2) |
| Previous minor limb amputation | 526 (2.6) | 2085 (16.3) |
| Previous major limb amputation | 379 (1.9) | 326 (2.5) |
| Comorbid conditions | ||
| Coronary artery disease | 3893 (19.4) | 2882 (22.5) |
| Cerebrovascular disease | 990 (4.9) | 713 (5.6) |
| Congestive heart failure | 6648 (33.1) | 4797 (37.5) |
| Hypertension | 16 271 (81.1) | 10 718 (83.8) |
| COPD | 6521 (32.5) | 4561 (35.7) |
| Chronic kidney disease | 3305 (16.5) | 2536 (19.8) |
| Dialysis | 2393 (11.9) | 1867 (14.6) |
Note: COPD = chronic obstructive pulmonary disease, PAD = peripheral artery disease, SD = standard deviation.
↵* Unless stated otherwise.
↵† Missing values: rural residence, 22 (0.1%) for any amputation and 17 (0.1%) for major amputation; neighbourhood income quintile, 244 (1.2%) for any amputation and 167 (1.3%) for major amputation.