Crude and adjusted odds ratios for overweight or obesity at 3 years of age with frequent household use of disinfectant and eco-friendly products
| Disinfectant products | Crude model (n = 675) Difference in BMI z score (95% CI) | Adjusted model* (n = 655) Difference in BMI z score (95% CI) |
|---|---|---|
| BMI z score coefficient | ||
| Disinfectant top 30th centile | 0.17 (0.01 to 0.33) | 0.11 (−0.02 to 0.25) |
| Lachnospiraceae (high v. low) | 0.28 (0.14 to 0.43) | 0.12 (−0.01 to 0.24) |
| BMI z score 1 year | 0.48 (0.42 to 0.53) | 0.45 (0.39 to 0.50) |
| Disinfectant Top 40th centile | 0.14 (−0.01 to 0.29) | 0.08 (−0.05 to 0.21) |
| Lachnospiraceae (high v. low) | – | 0.12 (−0.01 to 0.24) |
| BMI z score 1 year | – | 0.45 (0.39 to 0.50) |
| Disinfectant top 50th centile | 0.12 (−0.03 to 0.26) | 0.07 (−0.05 to 0.20) |
| Lachnospiraceae (high v. low) | – | 0.12 (−0.01 to 0.24) |
| BMI z score 1 year | – | 0.45 (0.39 to 0.50) |
| Overweight or obesity | OR (95% CI) | AOR (95% CI) |
| Disinfectant top 30th centile | 1.32 (0.78 to 2.25) | 1.32 (0.68 to 2.57) |
| Lachnospiraceae (high v. low) | 1.79 (1.06 to 3.03) | 1.18 (0.63 to 2.21) |
| BMI z score 1 year | 3.19 (2.27 to 4.30) | 3.01 (2.18 to 4.14) |
| Disinfectant top 40th centile | 1.58 (0.95 to 2.64) | 1.55 (0.81 to 2.96) |
| Lachnospiraceae (high v. low) | – | 1.14 (0.60 to 2.14) |
| BMI z score 1 year | – | 3.04 (2.20 to 4.20) |
| Disinfectant top 50th centile | 1.66 (0.98 to 2.80) | 1.55 (0.80 to 3.03) |
| Lachnospiraceae (high v. low) | – | 1.13 (0.60 to 2.13) |
| BMI z score 1 year | – | 3.00 (2.18 to 4.13) |
| Eco-friendly products | Crude model (n = 675) Difference in BMI z score (95% CI) | Adjusted model† (n = 655) Difference in BMI z score (95% CI) |
| BMI z score coefficient | ||
| Eco-friendly products 50th centile | −0.25 (−0.40 to −0.11) | −0.12 (−0.24 to 0.002) |
| Enterobacteriaceae (high v. low) | −0.001 (−0.15 to 0.14) | −0.014 (−0.14 to 0.11) |
| BMI z score 1 year | 0.48 (0.42 to 0.53) | 0.45 (0.40 to 0.50) |
| Overweight or obesity | OR (95% CI) | AOR (95% CI) |
| Eco-friendly products 50th centile | 0.36 (0.20 to 0.63) | 0.44 (0.22 to 0.86) |
| Enterobacteriaceae (high v. low) | 0.66 (0.39 to 1.10) | 0.51 (0.27 to 0.96) |
| BMI z score 1 year | 3.19 (2.37 to 4.30) | 3.01 (2.19 to 4.14) |
Note: AOR = adjusted odds ratio, BMI = body mass index, CI = confidence interval, OR = odds ratio.
↵* Adjusted for exposure to household disinfectant, household detergent and household smoke, maternal overweight, BMI z score at 1 year and Lachnospiraceae.
↵† Adjusted for exposure to household disinfectant, household eco-friendly products and household smoking, maternal overweight, BMI z score at 1 year and Enterobacteriaceae.