Baseline characteristics of 28 442 women who received fertility therapy*
| Characteristic | Fertility therapy; no. (%) of patients† | p value | |
|---|---|---|---|
| Failure n = 19 093 | Success n = 9349 | ||
| Age, yr, median (IQR) | 36 (32–39) | 34 (31–37) | < 0.001 |
| No. of fertility cycles (IQR) | 3 (1–5) | 3 (2–6) | < 0.001 |
| In vitro fertilization procedure | 2211 (11.6) | 968 (10.4) | < 0.001 |
| Rural residence | 787 (4.1) | 400 (4.3) | < 0.001 |
| Income quintile | < 0.001 | ||
| 1 (lowest) | 3202 (16.8) | 1048 (11.2) | |
| 2 | 3477 (18.2) | 1470 (15.7) | |
| 3 | 3718 (19.5) | 1877 (20.1) | |
| 4 | 4221 (22.1) | 2354 (25.2) | |
| 5 (highest) | 4416 (23.1) | 2591 (27.7) | |
| Unknown | 59 (0.3) | 9 (0.1) | |
| Prior obstetric delivery | 3167 (16.6) | 1700 (18.2) | < 0.001 |
| Any visit to emergency department in prior year | 903 (4.7) | 688 (7.4) | < 0.001 |
| Any hospital admission in prior year | 4193 (22.0) | 2277 (24.4) | < 0.001 |
| History of miscarriage | 3095 (16.2) | 1700 (18.2) | < 0.001 |
| History of stillbirth | 50 (0.3) | 63 (0.7) | < 0.001 |
| Hypertension, including gestational hypertension | 729 (3.8) | 656 (7.0) | < 0.001 |
| Diabetes, including gestational diabetes | 599 (3.1) | 964 (10.3) | < 0.001 |
| Hypercholesterolemia | 522 (2.7) | 98 (1.0) | < 0.001 |
| Smoking | 34 (0.2) | 6 (0.1) | 0.02 |
| Obesity | 435 (2.3) | 125 (1.3) | < 0.001 |
| Asthma | 792 (4.1) | 334 (3.6) | 0.02 |
| Neoplasm | 454 (2.4) | 90 (1.0) | < 0.001 |
| Depression | 585 (3.1) | 244 (2.6) | 0.03 |
| Systemic autoimmune rheumatic disease | 843 (4.4) | 367 (3.9) | 0.3 |
| Atrial fibrillation | 267 (1.4) | 165 (1.8) | 0.02 |
| Ischemic heart disease | 174 (0.9) | 62 (0.7) | 0.03 |
| Cardiomyopathy | 21 (0.1) | 32 (0.3) | < 0.001 |
| Cerebrovascular disease | 50 (0.3) | 27 (0.3) | 0.7 |
| Thromboembolic disease | 10 (0.1) | 9 (0.1) | 0.2 |
| Pulmonary circulation disease | 25 (0.1) | 13 (0.1) | 0.9 |
Note: IQR = interquartile range.
↵* Baseline characteristics were ascertained during the 2 years before the date of final fertility treatment except for history of live births, miscarriages and stillbirths, data for which were ascertained over the duration of available data.
↵† Unless stated otherwise.