Box 1: Risk of recurrence of venous thromboembolism according to provoking factor3,4
Provoking factorRisk of recurrence, %
Within 1 yr of stopping therapyWithin 5 yr of stopping therapy
Recent surgery13
Nonsurgical trigger (estrogen, pregnancy, leg injury, flight length > 8 h)515
Unprovoked venous thromboembolism1030
Cancer15