Table 1:

Relative risk of ischemic stroke before and after the start of α-blocker therapy (index date) among men aged 50 years or older

Period^*	No. of patients	No. of events	No. of person-days	IRR (95% CI)
Period^*	No. of patients	No. of events	No. of person-days	Unadjusted	Adjusted^†
Unexposed (ref)	7 502	6 119	6 862 065	1.00	1.00
Pre-exposure
Risk period 2 (−22 to −60 d)	7 345	526	281 361	1.96 (1.79–2.14)	1.99 (1.82–2.18)
Risk period 1 (−1 to −21 d)	7 495	428	155 939	2.83 (2.56–3.12)	2.87 (2.60–3.17)
Post-exposure
Risk period 1 (≤ 21 d)	7 493	214	155 467	1.42 (1.24–1.63)	1.40 (1.22–1.61)
Risk period 2 (22 to 60 d)	7 299	215	277 592	0.82 (0.71–0.93)	0.80 (0.70–0.92)

Note: CI = confidence interval, IRR = incidence rate ratio, ref = reference category.
↵* See the Methods and Figure 1 for details about the periods.
↵† Adjusted for age and development of atrial flutter/fibrillation.