| Risk factor | Approximate risk |
|---|---|
| Metastatic breast cancer | 30%3 |
| Aromatase inhibitor therapy | 1.4%–11.0% (any fracture)7 |
| Radiotherapy of breast or chest wall | 3.6%–4.5%6 |
| Prolonged use of bisphosphonates | 7.4%5 |
| Women aged 83 years or older | 40%4 |
| Early menopause or ovarian ablation secondary to adjuvant chemotherapy | Unknown |
| Tissue expansion in breast reconstruction using implants | Unknown |