Risk factor | Approximate risk |
---|---|
Metastatic breast cancer | 30%3 |
Aromatase inhibitor therapy | 1.4%–11.0% (any fracture)7 |
Radiotherapy of breast or chest wall | 3.6%–4.5%6 |
Prolonged use of bisphosphonates | 7.4%5 |
Women aged 83 years or older | 40%4 |
Early menopause or ovarian ablation secondary to adjuvant chemotherapy | Unknown |
Tissue expansion in breast reconstruction using implants | Unknown |