Lifestyle factor | No. (%) of participants n = 6458 | No. (%)who were nonadherent n = 3171‡ | Unadjusted OR (95% CI) | Adjusted OR (95% CI) | |
---|---|---|---|---|---|
Partial adjustment§ | Full adjustment¶ | ||||
Body mass index | n = 6301 | ||||
< 25 (ref) | 2550 (40.5) | 1300 (51.0) | 1.00 | 1.00 | 1.00 |
25–29.9 | 2675 (42.5) | 1276 (47.7) | 0.88 (0.79–0.98) | 0.88 (0.79–0.98) | 0.88 (0.79–0.99) |
≥ 30 | 1076 (17.1) | 518 (48.1) | 0.87 (0.75–1.00) | 0.86 (0.74–0.99) | 0.85 (0.73–0.99) |
Smoking status | n = 6138 | ||||
None (ref) | 2813 (45.8) | 1422 (50.6) | 1.00 | 1.00 | 1.00 |
Former | 2293 (37.4) | 1051 (45.8) | 0.83 (0.74–0.93) | 0.82 (0.74–0.92) | 0.83 (0.74–0.93) |
Current | 1032 (16.8) | 534 (51.7) | 1.05 (0.91–1.22) | 1.02 (0.88–1.18) | 0.99 (0.85–1.16) |
Mean alcohol consumption | n = 6297 | ||||
None (ref) | 937 (14.9) | 435 (46.4) | 1.00 | 1.00 | 1.00 |
Moderate | 4809 (76.4) | 2371 (49.3) | 1.11 (0.97–1.29) | 1.10 (0.95–1.27) | 1.09 (0.94–1.27) |
High | 551 (8.8) | 277 (50.3) | 1.13 (0.91–1.40) | 1.11 (0.89–1.38) | 1.13 (0.90–1.42) |
Extreme drinking occasions | n = 6278 | ||||
No (ref) | 5905 (94.1) | 2881 (48.8) | 1.00 | 1.00 | 1.00 |
Yes | 373 (5.9) | 193 (51.7) | 1.10 (0.89–1.36) | 1.07 (0.86–1.33) | 1.01 (0.81–1.27) |
Physical activity | n = 6274 | ||||
Active (ref) | 2301 (36.7) | 1124 (48.8) | 1.00 | 1.00 | 1.00 |
Moderate | 2105 (33.6) | 1034 (49.1) | 1.01 (0.90–1.14) | 1.02 (0.91–1.15) | 1.04 (0.92–1.18) |
Low | 1868 (29.8) | 913 (48.9) | 1.01 (0.89–1.14) | 1.01 (0.90–1.15) | 1.03 (0.90–1.18) |
No. of lifestyle risks | n = 6439 | ||||
0 (ref) | 2996 (46.5) | 1438 (48.0) | 1.00 | 1.00 | 1.00 |
1–2 | 3216 (49.9) | 1618 (50.3) | 1.10 (0.99–1.21) | 1.07 (0.97–1.19) | 1.07 (0.96–1.18) |
3–4 | 227 (3.5) | 105 (46.3) | 0.93 (0.71–1.22) | 0.89 (0.67–1.17) | 0.87 (0.66–1.15) |
Note: CI = confidence interval, OR = odds ratio, ref = reference group.
↵* Nonadherence = < 80% of days covered by filled prescriptions.
↵† Without hypertension, heart failure, coronary artery disease, diabetes, stroke or arrhythmias.
↵‡ Percentages are based on row totals.
↵§ Adjusted for sex, age and year of statin initiation.
↵¶ Adjusted for factors in the first model plus education, marital status, residential region, suboptimal self-rated health, use of antidepressants, cancer and other lifestyle factors; 624 participants were excluded from this model because of missing data on at least 1 lifestyle factor (except for the no. of lifestyle risks) or covariate.