Sensitivity analysis | No. of women | No. of cases/person-years | Multivariable RR (95% CI)* |
---|---|---|---|
Follow-up until end of 2003 | |||
Never user | 14 721 | 43/89 916 | 1.00 (ref) |
Ever user | 16 773 | 57/103 756 | 1.52 (1.00–2.29) |
Women aged > 60 yr | |||
Never user | 9 080 | 76/105 441 | 1.00 (ref) |
Ever user | 7 362 | 78/88 606 | 1.42 (1.03–1.97) |
Women not currently using HRT† | |||
Never user | 14 721 | 98/178 430 | 1.00 (ref) |
Past user with duration < 5 y | 2 124 | 14/26 440 | 1.16 (0.66–2.04) |
Past user with duration ≥ 5 y | 918 | 10/11 305 | 1.62 (0.84–3.13) |
Note: CI = confidence interval, HRT = hormone replacement therapy, ref = reference group, RR = relative risk.
↵* Adjusted for the same covariables as the multivariable model (Table 2): age at menopause (< 51 or ≥ 51 yr), education (less than high school, high school or university), smoking status (never, past [as < 10 or ≥ 10 pack-years] or current [as < 20 or ≥ 20 pack-years]), body mass index (< 25, 25–29 or ≥ 30), alcohol intake (quartiles [g/d]) and vegetable consumption (quartiles [servings/d]).
↵† Sum of categories is less than the total number of women not currently using HRT because data on duration of use were missing for 618 women (including 12 cases).