Medical history and medication use
| Variable | % (no.) of patients | p value* | ||
|---|---|---|---|---|
| All patients n = 2568 | Stable angina n = 1339 | Acute coronary syndrome n = 1229 | ||
| Medical history | ||||
| Family history of heart disease | 21.1 (533/2526) | 23.7 (315/1329) | 18.2 (218/1197) | < 0.001 |
| Hypertension | 80.9 (2044/2527) | 82.4 (1095/1329) | 79.2 (949/1198) | 0.04 |
| Atrial fibrillation | 12.5 (312/2499) | 12.5 (164/1313) | 12.5 (148/1186) | 0.99 |
| Hyperlipidemia | 65.3 (1649/2526) | 72.2 (960/1329) | 57.6 (689/1197) | < 0.001 |
| Diabetes mellitus | 33.5 (847/2526) | 33.9 (450/1328) | 33.1 (397/1198) | 0.7 |
| Current smoker | 39.4 (995/2524) | 38.9 (517/1328) | 40.0 (478/1196) | 0.6 |
| Previous MI | 7.0 (65/926) | 6.9 (37/534) | 7.1 (28/392) | 0.9 |
| Previous revascularization | 11.3 (105/926) | 12.9 (69/534) | 9.2 (36/392) | 0.07 |
| Medication use | ||||
| ASA | 65.5 (1537/2345) | 75.2 (933/1241) | 54.7 (604/1104) | < 0.001 |
| Clopidogrel | 28.8 (675/2343) | 32.9 (408/1240) | 24.2 (267/1103) | < 0.001 |
| ACE inhibitor or ARB | 59.8 (1402/2345) | 68.4 (849/1241) | 50.1 (553/1104) | < 0.001 |
| Beta-blocker | 65.0 (1522/2343) | 74.1 (920/1241) | 54.6 (602/1102) | < 0.001 |
| Statin | 54.5 (1277/2344) | 65.6 (814/1240) | 41.9 (463/1104) | < 0.001 |
| Calcium-channel blocker | 18.4 (239/1300) | 20.2 (127/630) | 16.7 (112/670) | 0.1 |
| Diuretic | 38.3 (498/1300) | 40.6 (256/630) | 36.1 (242/670) | 0.09 |
| Aldosterone antagonist | 2.8 (36/1299) | 3.3 (21/630) | 2.2 (15/669) | 0.2 |
Note: ACE = angiotensin-converting enzyme, ARB = angiotensin-receptor blocker, ASA = acetylsalicylic acid, MI = myocardial infarction.
↵* χ2 test for comparison of patients with stable angina and those with acute coronary syndrome.