Vitamin D and parathyroid hormone levels in offspring and controls
| Variable | Mean (95% CI) | p value | |
|---|---|---|---|
| Offspring n = 1038 | Controls n = 461 | ||
| 25(OH) vitamin D,*nmol/L | |||
| Model 1† | 64.3 (63.1– 65.4) | 68.5 (66.0–71.1) | 0.002 |
| Model 2‡ | 64.3 (63.1– 65.4) | 68.4 (66.0–71.0) | 0.002 |
| Sensitivity analyses | |||
| Supplement users excluded§ | 64.3 (63.1–65.4) | 68.4 (66.0– 1.0) | 0.002 |
| Matched analysis¶ | 64.5 (61.4–69.5) | 70.0 (65.6–74.7) | 0.001 |
| Sun exposure adjusted** | 67.7 (62.7–73.1) | 72.0 (66.4–78.2) | 0.02 |
| Parathyroid hormone,††pg/mL | |||
| Model 1† | 39.2 (38.5–39.9) | 39.6 (38.1–41.0) | 0.7 |
| Model 2‡ | 39.3 (38.6–40.0) | 39.3 (37.8–40.7) | 0.9 |
| Sensitivity analyses | |||
| Supplement users excluded§ | 39.3 (38.6–40.0) | 39.3 (37.8–40.7) | 0.9 |
| Matched analysis¶ | 37.4 (35.0–39.9) | 39.1 (36.5–41.6) | 0.049 |
Note: CI = confidence interval.
↵* Vitamin D presented as geometric means with 95% CI.
↵† Model 1: adjusted for sex and age.
↵‡ Model 2: model 1 plus adjustment for body mass index, month of the year blood was drawn, habitual vitamin D intake via food, use of multivitamin supplements, use of vitamin D supplements, and creatinine level.
↵§ Used model 2 for analysis; included 727 offspring and 332 controls who did not use multivitamin and/or vitamin D supplements.
↵¶ Used model 2 for analysis; included 430 offspring and 430 controls, who were partners.
↵** Used model 2 for analysis, with additional adjustment for tanning bed use and sun exposure; included 279 offspring and 275 controls.
↵†† Parathyroid hormone levels presented as means with 95% CI.