Odds ratios of type 2 diabetes mellitus during the 10-year follow-up period, by baseline level of plasma bicarbonate
| Group or model | Quartile (plasma bicarbonate level, mmol/L); OR (95% CI)* | p for linear trend | |||
|---|---|---|---|---|---|
| Quartile 1 (< 20.6) | Quartile 2 (20.6–22.3) | Quartile 3 (22.4–23.9) | Quartile 4 (> 23.9) | ||
| Cases, no. | 188 | 165 | 139 | 138 | |
| Controls, no. | 189 | 176 | 183 | 182 | |
| Model | |||||
| 1† | Referent | 0.93 (0.69–1.25) | 0.75 (0.55–1.01) | 0.74 (0.55–1.01) | 0.03 |
| 2‡ | Referent | 0.92 (0.67–1.25) | 0.70 (0.51–0.97) | 0.75 (0.54–1.05) | 0.04 |
Note: CI = confidence interval, OR = odds ratio.
↵* Unless otherwise stated.
↵† Adjusted for matching factors: age at blood draw (continuous), ethnic background (white v. non-white) and fasting status at blood draw (binary). n = 630 cases and 730 controls.
↵‡ Adjusted for matching factors, body mass index (continuous), history of hypertension (binary) and plasma creatinine (< 0.6 mg/dL, 0.6–0.8 mg/dL, > 0.8 mg/dL). n = 629 cases and 729 controls. One case and one control in this model were missing data for body mass index.